Foda Spermidine: Shin Ya cancanci Tsammani?

Jikin dan adam ya kunshi gabobi da kyallen takarda, wadanda su kuma sun hada da sassan aikin jiki, wato sel. Kusan kowane tsarin nazarin halittu ana yinsa kuma ana kiyaye shi a matakin salula, kuma sakamakon waɗannan ana hasashen su akan kyallen takarda da gabobin jiki. Farawa tare da ƙwayoyin sel, ƙwayoyin ɗan adam a duk lokacin haɓakawa yayin lokacin haifuwa suna rarrabe cikin sel daban -daban waɗanda ke ƙaura zuwa sassan jiki daban -daban kuma suna yin ayyuka daban -daban daidai gwargwado.

Kwayoyin suna aiwatar da ayyuka daban -daban kamar metabolism da homeostasis, duk da haka, ba za su iya yin hakan da kan su ba kuma suna buƙatar sunadarai daban -daban, enzymes, da siginar mahadi don taimaka musu cimma nasarar da ake so.

Nau'in sel daban -daban suna da tsawon rayuwa daban -daban kuma da zarar sun kammala wannan lokacin, suna shiga tsufa ko tsufa, iri -iri, bayan haka sun lalace ko ƙasƙantar da su, suna alamar ƙarshen rayuwarsu.

Yayin da mutum ya tsufa, ayyukan salula suna canzawa da farko, wanda ke haifar da alamun zahiri na tsufa, ƙarshe. Koyaya, an gudanar da nau'ikan bincike da yawa don yin nazari da fahimtar yadda ake ƙara tsawon rayuwar sel kuma a sakamakon haka, mutane. A sakamakon waɗannan karatun, an gano wakili na tsawon rai wanda kuma ya faru ya zama ɗaya daga cikin manyan mahaɗan waɗanda ke da mahimmanci don kula da ayyuka daban -daban na sel. Ana samun wannan fili a yalwa a jikin mutum kuma ana kiran sa da suna spermidine.

Inganta lafiyar ɗan adam da haɓaka haɓakar rayuwar sel, kuma a sakamakon haka, ɗan adam, shine babban aikin wannan fili, kodayake yana shiga cikin nau'ikan sunadarai da halayen rayuwa a cikin jiki.

Menene Spermidine Foda?

Spermidine shine polyamine da aka samo ta halitta wanda yake da mahimmanci ga aikin al'ada na jiki duka. Kodayake bai taka rawar gani ba wajen kiyayewa ko samar da maniyyi, ana kiransa mahadi na maniyyi saboda da farko an gano shi a cikin maniyyi. An hada shi a jikin mutum ta hanyar ayyukan enzyme, spermidine synthase akan fili, putrescine.

Za a iya kara narkar da maniyyi zuwa maniyyi, da sauran polyamines, gami da tsarin isomer na maniyyi, thermospermine. An samo shi a cikin ribosomes na tantanin halitta, babban aikin wannan fili shine haɓaka autophagy wanda ke ba da damar sabuntawar sel a cikin jikin mutum. Yana iya aiwatar da waɗannan ayyukan ta hanyar haifar da autophagy a matakin salula a cikin jiki, maimakon a matakin sama.

Ganin babbar rawar da maniyyi ke takawa a cikin jiki, sarrafa matakan al'ada dole ya zama mai mahimmanci. Koyaya, an gano cewa matakan Spermidine a cikin jiki suna fara raguwa a matsayin shekaru ɗaya, wanda zai iya rage ingancin aikin da ake aiwatar da ayyuka daban -daban na rayuwa. Duk wannan yana haifar da raguwar ƙarfin jikin ɗan adam wanda galibi ana dora laifin akan tsufa, amma ba tsufa kai tsaye ke haifar da shi ba amma sakamakon lalacewar mahimman abubuwan mahaɗan a jikin ɗan adam.

Spermidine foda shine ƙarin nau'in Spermidine wanda ke da niyyar cika ɗakunan jikin wannan aliphatic polyamine da haɓaka aikin jiki.

Tarihin Spermidine

Ana kiran Spermidine irin wannan saboda da farko an ware shi daga maniyyi amma tun daga lokacin an gano cewa ana rarraba shi sosai a jikin ɗan adam kuma yana taka rawa daban -daban a sassa daban -daban na jiki. Kodayake yana da mahimmanci a lura cewa yana da babban aiki guda ɗaya a cikin jiki wanda shine yaduwar sel da sabuntawa, ta hanyar haɓaka autophagy. Yana daya daga cikin manyan wakilan tsawon rai a cikin mutane da sauran dabbobi masu shayarwa.

Antoni van Leeuwenhoek ne ya fara gano wakilin tsawon rai a cikin maniyyin ɗan adam, a cikin 1678 kodayake ya bayyana shi a matsayin lu'ulu'u. Sai bayan kusan shekaru 200 aka gano cewa lu'ulu'u da Leeuwenhoek ya gani sun kasance maniyyi, magajin Spermidine. Duk da haka, har yanzu ba a san tsarin sinadarin spermidine da maniyyi ba kuma sai a shekarar 1924 aka gano tsarin sinadarin tare da yin nazari dalla -dalla.

Kara nazarin tsarin maniyyi ya bayyana ƙarin ayyukansa da sifofi na musamman a jikin ɗan adam. An gano cewa spermidine, kamar kowane polyamine, barga ce mai ƙarfi wacce ba ta narkewa ko amsawa a cikin mawuyacin yanayi. Bugu da ƙari, an gano spermidine yana da cajin da ya dace wanda ke ba shi damar ɗaure ga ƙwayoyin da ba su da kyau kamar RNA da DNA.

Bugu da ƙari, an gano cewa Spermidine yana samuwa a yalwace a cikin jikin ɗan adam, tare da matakan fara raguwa kamar shekaru ɗaya, kusan lokaci guda matakan collagen da elastin za su ragu. A farkon farkon rayuwa, mutane suna karɓar maniyyi ta hanyar madarar nono ko ƙirar jariri kuma yayin da suka tsufa, suna karɓar maniyyi daga tushen abinci daban -daban. Duk da haka, asalin halittar spermidine bai isa ya cika shagunan mahallin da ake zubar ba saboda raguwar samar da polyamine.

A cikin irin waɗannan lokuta, an gudanar da nau'ikan bincike da yawa don yin nazarin yadda za a iya cika shagunan da ƙarin abubuwan Spermine waɗanda ke ɗauke da Spermidine trihydrochloride foda a matsayin mai aiki mai aiki da aka gano shine mafita ga wannan matsalar. A halin yanzu ana samun kariyar Spermidine kuma an yarda da su azaman kari na tsawon rai.

Aikin Spermidine a Jikin Dan Adam

Abubuwan kari na Spermidine suna taka rawa iri ɗaya kamar yadda maniyyi zai kasance a cikin jiki wanda shine dalilin da ya sa yana da mahimmanci a san mahimman ayyukan Spermidine a jikin ɗan adam. An gano Spermidine yana da mahimmanci don hana hana nitric oxide synthase ko nNOS, cewa kamar yadda sunan ya nuna ana bayyana shi kawai a cikin jijiyoyin jiki da na tsakiya. Babban aikin nNOS shine saka idanu da daidaita sautin vasomotor da daidaita hawan jini na tsakiya tare da kula da filastik synaptic a cikin neurons na tsakiya.

An hana hana nNOS ta duka spermidine endogenous da spermidine yana da tasirin neuroprotective, gami da tasirin anti-depressive. Bugu da ƙari, hana nNOS yana da alhakin raguwa mai mahimmanci a cikin naƙasasshiyar tsoka da lalacewar jijiyoyin jijiyoyin jiki da ke yin wannan aikin na maniyyi aikin kariya.

An nuna Spermidine, tare da sauran polyamines, suna da tasiri iri ɗaya akan sake zagayowar tantanin halitta kamar abubuwan haɓakawa waɗanda kuma ke tallafawa babban aikinsa; autophagy da tsawon rai. Bugu da ƙari, spermidine yana ɗaure zuwa mahadi daban -daban don tallafawa ayyuka daban -daban na fili.

Amfani da Spermidine Foda

Ana amfani da Spermidine foda azaman kari don hana nau'in ciwon daji daban -daban, musamman carcinoma hepatocellular da fibrosis hanta. Yawancin mutane sun zaɓi ɗaukar foda spermidine a matsayin kari saboda iyawarsa ba kawai inganta tsawon rai ba har ma saboda tasirin kariya na fili.

Fa'idodin Spermidine Foda azaman kari

An yi amfani da Spermidine azaman kari a kwanan nan amma binciken kimiyya ya tallafa masa sosai wanda ya gano yana da fa'idodi da yawa a jikin ɗan adam. Wasu daga cikin manyan fa'idodin spermidine foda azaman kari shine:

· Ingantaccen Ƙwaƙwalwa da Ingantaccen Aiki

Amfani da ƙwayar maniyyi yana da alaƙa da kaddarorin neuroprotective kodayake wannan ba shine babban fasalin da ke da alhakin tashe -tashen hankulan mahaɗan ba. Kyakkyawan tasirin Spermidine akan kwakwalwa da sanin yakamata shine sakamakon kaddarorin sa na kumburi wanda ke hana kumburi a cikin neurons, saboda haka yana rage haɗarin rikicewar ƙwayoyin cuta da yawa kamar cutar Parkinson da cutar Alzheimer.

Binciken da aka yi kwanan nan ya mai da hankali don yin nazarin tasirin wannan polyamine na musamman saboda polyamines na iya samun tasirin neuroprotective da neurotoxic. Anyi nazarin Spermidine a cikin samfuran dabbobi tare da cututtukan neurodegenerative, musamman neurodegeneration sakamakon cin mutuncin hypoxic-ischemic. An gano cewa wannan cin mutuncin ya haifar da kumburi ta hanyar rage ayyukan nitric oxide a cikin kwakwalwa. Koyaya, amfani da spermidine ya haifar da raguwar kumburi yayin da aka gano cewa yana haɓaka enzyme, nitric oxide synthase a cikin kwakwalwa wanda yake da mahimmanci don haɗin nitric oxide, kuma a ƙarshe, maganin kumburi. Wannan binciken ya tabbatar da tasirin kumburi na spermidine da wanda ya gaje shi, spermine a vivo a cikin samfuran dabbobi.

Anyi irin wannan binciken akan samfuran dabbobi tare da raunin motsi da raguwar matakan dopamine, sakamakon bayyanar da rotenone. Bayyanar Rotenone a cikin waɗannan samfuran yana haifar da raunin motsi kwatankwacin ƙarancin motar da ake gani a cikin mutanen da ke fama da cutar Parkinson. Masana kimiyya da ke gudanar da binciken sun gano cewa spermidine yana da kaddarorin antioxidant waɗanda ke taimakawa ceton ƙwayoyin dopaminergic waɗanda rotenone ya shafa a cikin berayen yayin da suke yaƙar tasirin cytokines proinflammatory da oxidative stress. Waɗannan matsin lamba suna haifar da lalacewar jijiyoyin jiki kuma suna haifar da raguwar alamun masu ba da labari kamar serotonin, norepinephrine, da dopamine.

Amfani da Spermidine ya kubutar da waɗannan neurons a cikin ƙirar dabbobin kuma ya juyar da raunin motar da ke haifar da bayyanar rotenone, saboda haka, yana tabbatar da hasashen cewa spermidine yana da kaddarorin neuroprotective.

Hakanan, an gudanar da bincike don nazarin tasirin spermidine na abinci akan aikin hankali. Sanannen abu ne cewa tsufa yana da mummunan tasiri akan aikin fahimi, duk da haka, ana hasashen cewa za a iya yin illa ga waɗannan tasirin ta hanyar amfani da kariyar ƙwayar maniyyi.

Lokacin nazarin samfuran dabbobi waɗanda aka ba da kariyar maniyyi, an gano cewa yana iya ƙetare shingen kwakwalwa na jini da haɓaka aikin hippocampal da aikin mitochondrial a cikin kwakwalwa. Wannan yana da mahimmanci musamman kamar yadda hippocampus yake da mahimmanci don ƙirƙirar ƙwaƙwalwar ajiya da sanin yakamata, kuma haɓaka aikinsa na iya zama da fa'ida musamman wajen yaƙar ɓarna na ilimin halittu da cututtukan cututtukan aikin hippocampal.

Ainihin, spermidine yana da kayan kumburi da kaddarorin antioxidant tare da ikon ƙetare katangar-jini wanda ke ba shi damar zama wakilin neuroprotective a jikin ɗan adam.

· Abubuwan Kayayyakin Tsofaffi tare da Ƙaruwar Ciwon Kai

Spermidine wani sinadari ne da ake samu a jikin mutum wanda ke taka muhimmiyar rawa a tsawon rayuwar sel. Yana ɗaure zuwa DNA, RNA, da sauran ƙwayoyin da aka caje su waɗanda ke ba shi damar shiga cikin matakai na rayuwa da yawa. Sakamakon waɗannan matakai shine haɓaka ƙwayar sel, haɓaka sel, da rigakafin tsufa na jiki. Koyaya, ba zai iya magance tasirin tsufa da mutuwar sel a matsayin tsufa ba saboda matakan spermidine sun fara raguwa daga tsakiyar shekaru.

Tsufa wani tsari ne mai rikitarwa na kwayoyin halitta wanda ke faruwa don mayar da martani ga matsi daban -daban da abubuwan da ke haifar da mutuwar sel. Amfani da kayan abinci na maniyyi na foda na abinci ana tsammanin yana da tasirin tsufa akan jikin ɗan adam ta hanyar ikon sa autophagy. A taƙaice, autophagy tsari ne na salon salula, wanda idan aka fassara yana nufin 'cin kan mutum'. Wannan tsari ne ke da alhakin narkar da gabobin jikin da ba su aiki ko gurɓatattun abubuwa da sunadarai, bi da bi, wanda ke haifar da lalata sel waɗanda ba za su iya sake yin ayyukan da ake buƙata ba. Duk da cewa aikinsa yana da cutarwa, autophagy yana da tasirin kariya akan sel yayin da yake cire ƙwayoyin da basu da tasiri.

Yin amfani da spermidine trihydrochloride foda yana da alaƙa da haɓaka autophagy a cikin jikin ɗan adam wanda ke taimakawa cikin matakan tsufa yayin da yake cire ƙwayoyin da ba sa aiki, yana haɓaka samar da sabbin sel masu aiki. Wannan sabuntawar salula yana da mahimmanci don hana ƙwayoyin da ba sa aiki su ci gaba da kasancewa a cikin jiki wanda ke haifar da tasirin tsufa.

Shigar da ciwon kai ta hanyar maniyyi na foda shima yana taka rawa a cikin garkuwar jiki, musamman a cikin sel T. Wani binciken da aka yi kwanan nan ya gano cewa wakilan haɓaka autophagy, kamar spermidine, na iya zama da fa'ida wajen inganta martanin marasa lafiya ga alluran rigakafi. Masu binciken suna da niyyar isar da wannan bayanin ga cibiyoyin rigakafin cutar kuma suna fatan yin amfani da maniyyi na abinci ya zama babban jadawali ga tsofaffi marasa lafiya da ake yiwa allurar rigakafi.

Baya ga autophagy, spermidine kuma yana da kaddarorin tsufa sakamakon wasu hanyoyin da ke taimakawa hana shida daga cikin alamun tara na tsufa a jikin mutum. Yayin da mutum ya tsufa, ƙwayoyin sel suna rasa ikon su na rarrabewa cikin nau'ikan sel daban waɗanda suka mutu, suka yi ƙaura, ko suka rasa ikon aikin su. Wannan yana haifar da canje -canje marasa canzawa a jikin ɗan adam kamar furfura gashi kuma gabaɗayan tsarin ana kiransa gajiyawar sel. An hana ko yakar wannan alamar tsufa ta hanyar kariyar maniyyi foda wanda zai iya ƙara tsawon rayuwar sel.

Canjin Epigenetic wata alama ce ta tsufa wanda ke nufin canje -canje a cikin sassan kwayoyin halittar tantanin halitta tare da tsarin tantanin halitta da ilimin halittar jiki sakamakon fallasa abubuwa daban -daban na muhalli. Waɗannan gubobi na muhalli suna haifar da canje -canje a cikin sel waɗanda ke cutar da kwayar cutar da ke haifar da tsufa da farko na sel kuma a ƙarshe, mutuwar sel. Hakanan ana yaƙar wannan alamar ta amfani da maniyyi kamar yadda aka sani don haɓaka sabuntawar salula.

Yayin da sel suka tsufa, suna jagorantar mafi yawan kuzarin su don kiyaye kai wanda ke haifar da canza mummunan sadarwa mara kyau kamar yadda kwayar cutar zata lalata wasu ƙwayoyin da ke ƙoƙarin kiyaye lafiyar ta da haɓaka tsawon rai. Koyaya, wannan, a cikin dogon lokaci, na iya yin illa ga lalacewar nama da lafiyar gabobin jiki, wanda shine bincike akai -akai a cikin mutanen da suka tsufa. Koyaya, amfani da maniyyi yana da alaƙa da rage canjin sadarwa tsakanin sel don inganta tsawon rayuwar dukkan sel, ba tare da cutar da wasu sel a cikin nama ba.

Sunadaran suna taka muhimmiyar rawa a cikin sel kuma suna da mahimmanci don aiwatar da dukkan ayyukan rayuwa. Ana buƙatar gina furotin da kyau a cikin jiki don tabbatar da ingantaccen aikin jiki tare da kula da homeostasis. Tare da shekaru, sunadarai suna rasa ikon su na riƙe takamaiman tsarin su wanda ke ba su damar yin takamaiman ayyuka. Matsalolin muhalli suna shafar waɗannan sunadaran da hanyoyin da ke haifar da samarwa da kiyaye waɗannan tsarin furotin. Wannan ana kiransa asarar proteostasis kuma alama ce mai mahimmanci na tsufa.

Tsawon rayuwar tantanin halitta ya ƙare kuma tantanin halitta yana shiga lokacin tsufa lokacin da telomeres na tantanin halitta ya yi gajarta don tantanin halitta ya kasa rarrabuwa. Telomeres suna ci gaba da raguwa yayin da tantanin halitta ke rarrabuwa kuma a ƙarshe ya kai girman da ya yi ƙanƙanta don ba da damar ƙara rarraba sel, wanda ke haifar da yin shiru na telomere. Bayan wannan, tantanin halitta ba zai iya rarrabuwa ba kuma a ƙarshe zai mutu. Takarar Telomere muhimmin alama ce ta tsufa wanda aka yi nazari da bincike sosai don haɓaka mahaɗan tsufa. Ana samun Spermidine a cikin jiki kuma yana da alhakin adawa da tasirin telomere, yana barin sel suyi rarrabuwa cikin yardar rai na tsawon lokaci.

Spermidine yana inganta ayyukan mitochondrial kuma yana rage tasirin oxyidative a jiki. Wannan wata alama ce ta tsufa wanda za a iya adawa da shi ta amfani da kariyar maniyyi na foda.

· Yana Hana Wasu Ciwon Kansar Ci Gaba

An yi imanin Spermidine yana da tasirin anti-neoplastic kamar yadda aka gano cewa mutanen da ke shan maniyyi suna da ƙarancin haɗarin haɓaka ƙwayar hepatocellular carcinoma da yanayin da ya gabata, fibrosis hanta. Wani bincike na baya -bayan nan ya gano cewa spermidine yana iya dakatar da fibrosis hanta daga haɓaka har ma a cikin dabbobin dabbobin da aka fallasa su ga sunadarai tare da ikon samar da fibrosis na hanta.

Wani binciken lura ya gano cewa amfani da maniyyi yana da yuwuwar hana kansar hanji, kodayake ana buƙatar ƙarin bincike kafin a ƙara shi cikin jagororin jiyya da rigakafin.

Bugu da ƙari, an gano cewa amfani da maniyyi a cikin marasa lafiyar chemotherapy da ke shan magani don cutar kansa da ciwon daji na ciki ya taimaka inganta sakamakon magani da haɓaka abubuwan da ke haifar da cutar kansa.

· Kula da Rhythm na Circadian da ya dace

Sau da yawa ana tallata kariyar Spermidine azaman bacci yana farawa da kiyaye samfura yayin da yake mai da hankali kan haɓaka yanayin circadian. Wani binciken da aka yi akan samfuran dabbobi ya gano cewa tsoffin beraye, tare da ƙananan matakan maniyyi a jikinsu, suna da saurin circadian rhythm wanda galibi yana tasowa azaman rashin bacci. Lokacin da aka haɗa shi da foda na maniyyi, an gano waɗannan tsoffin beraye suna da ƙarar circadian mai aiki tare da sake zagayowar circadian.

· Kyawun Gashi, Nails, da Fata

Spermidine yana sake sabunta sel kuma yana haɓaka ci gaban sel mai lafiya wanda ke juyar da tasirin tsufa akan fata, gashi, da farce. Tsufa yana ɗaukar nauyi akan bayyanar fatar fatar, tare da tsufa fata tana bayyana wrinkled da saggy tare da ƙyallen fata. Ana iya juyar da waɗannan tasirin ta amfani da kariyar spermidine waɗanda aka ba da shawarar sosai don ƙawata gashi, kusoshi, da fata.

Waɗanne Abinci ne Mai wadata a cikin Spermidine Foda?

Ana samun Spermidine ta halitta a cikin tushen abinci da yawa, galibi waɗanda ke cikin abincin Bahar Rum. An ambaci tushen abinci na spermidine a ƙasa:
  • Binne
  • Kwayar hatsi
  • Koren Barkono
  • Broccoli
  • Naman kaza
  • Farin kabeji
  • Chees (iri daban -daban suna da abun ciki daban -daban na maniyyi)
  • Natto
  • Shiitake naman kaza
  • Amaranth hatsi
Ganyen Alkama wata muhimmiyar tushen spermidine ne, wanda aka adana a cikin ƙarshensa. Muhimmancin wannan tushen abinci na maniyyi shine cewa galibi ana amfani da shi wajen samar da kariyar maniyyi azaman tushen mahallin.

Menene Cire Kwayar Spermidine na Alkama?

Spermidine a matsayin kari na abinci ya samo asali ne daga ƙwayar alkama wacce ke da ƙima a cikin maniyyi. Don ƙera wannan ƙarin daga tsiran alkama, ana kula da ƙwayar alkama don fitar da maniyyin sa daga endospore. Ana samar da tsirrai na alkama mai ƙamshi ta hanyar magance abin da aka samo daga ƙwayar alkama tare da cire yisti. Har ila yau an san shi da Fermented Extract Of Whem Germ, FWGE, MSC, Triticum Aestivum Germ Extract, da Triticum Vulgare Germ Extract, wannan samfurin shine abin da ke ba da kayan abinci na abinci na maniyyi tare da maniyyi.

Amfani da Cire Kwayar Kwayar Spermidine

A spermidine alkama jam tsantsa bada shawarar ga mutane so zuwa baya sakamakon tsufa a jikin su, kamar graying na gashi, wrinkling na fata, da kuma rage samar da makamashi. Wasu daga cikin sauran amfanin FGWE sun haɗa da:
  • Kunar rana: Kamar yadda spermidine ke iya haɓaka haɓakar sel, yaduwa, da sake sabuntawa, an yi imanin cewa ƙwayoyin da lalacewar UV ta haifar na iya amfana daga tasirin spermidine. Waɗannan sel ana hasashen za su yi aikin autophagic sakamakon amfani da maniyyi, wanda daga nan zai haifar da sabbin ƙwayoyin da za a samar don magance kunar rana a jiki.
  • Rigakafin zazzabi a cikin marasa lafiyar chemotherapy: spermidine yana taka muhimmiyar rawa a cikin tsarin garkuwar jiki ta hanyar kaddarorin sa na autophagic, kuma waɗannan kaddarorin ne ke taimakawa spermidine germ alkama cire foda don haɓaka lalata ƙwayoyin cutar chemotherapy da ke haifar da haifar da haɓaka sabbin sel. Wannan yana taimakawa sake farfado da ƙwayoyin T masu lafiya da aiki a cikin jiki wanda ke taimaka wa waɗannan marasa lafiya su yaƙi kamuwa da cututtuka.
  • Gudanar da cututtukan autoimmune: Spermidine yana da kaddarorin kumburin kumburi wanda ke taimakawa wajen gudanar da cututtukan autoimmune tare da fasali masu kumburi.
Mafi yawan ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar cuta. Bugu da ƙari, an yi imanin cewa amfani da kari na maniyyi na yau da kullun yana da fa'ida wajen hana ci gaban cutar kansa da fari, kuma yana iya jujjuya illar cutar kansa yayin da yake sarrafa illolin cutar kansa.

Hanyoyin Hanyoyin Amfani da Spermidine Foda

Spermidine polyamine ne wanda ake samu a zahiri a cikin jiki, wanda yawan sa ba shi da illa a jikin ɗan adam. Koyaya, ƙananan matakan spermidine a cikin jiki suna da alaƙa da tsufa da wuri, raguwar ƙwaƙwalwar ajiya da aikin fahimi, tare da rage kwanciyar hankali na tsarin da amincin fata. Hakanan yana haifar da raunin aikin mitochondrial wanda daga baya yayi ƙarin tasirin tsufa a jiki.

Abubuwan kari na Spermidine waɗanda ake ƙera su ta amfani da ƙwaƙƙwaran ƙwayar alkama da kuma bin duk ƙa'idodin aminci da yarjejeniya kuma ana ɗaukarsu amintattu ne ga amfanin ɗan adam. Anyi nazarin waɗannan abubuwan kari sosai kuma har yanzu ba a gano wani sakamako mai mahimmanci ba, saboda haka kira don ƙarin bincike da za a kafa. Yana da mahimmanci a lura cewa har yanzu ba a ba da rahoton guba na maniyyi

Me yasa Zaɓi Masana'antar ƙera Mashin ɗinmu na Spermidine?

Spermidine foda shine madaidaicin fili wanda shima ake samu a jiki. A cikin masana'antar masana'antar mu, ana samar da foda na maniyyi a cikin ƙwararre, dakin gwaje -gwaje na bakararre don tabbatar da amincin samfurin. An ƙera samfurin ta bin ƙa'idodi da ƙa'idodin aminci don tabbatar da fa'idodin mafi girma na mahaɗin spermidine yayin da kuma rage yuwuwar gurɓatawa ko ɗaukar mahaɗan tare da wasu samfuran. Haka kuma, samfuran ana gwada su ne bayan samarwa don tabbatar da amincin su, inganci da ƙarfin su. Duk wani samfurin maniyyi wanda bai wuce wannan gwajin ba an shirya shi kuma an shirya shi don siyarwa amma a mayar da shi, kuma sauran samfuran a cikin rukunin guda ana ba su horo mai yawa don tabbatar da cewa babu matsala tare da ingancin ƙwayar maniyyin.

Spermidine foda yana samuwa da yawa a masana'antar mu, kodayake ana siyarwa ne kawai don dalilai na bincike da ci gaba, ko don aikace -aikacen sa a fagen magunguna. Spermidine tsaka -tsakin magunguna ne kuma muhimmin substrate a cikin sunadarai da magunguna. Don waɗannan dalilai, ana buƙatar ƙimar Spermidine mai inganci, wanda ke samuwa a masana'antar masana'anta ta Spermidine.

Spermidine foda daga wuraren masana'antunmu yana samuwa don siye a cikin fakiti da yanayi daban -daban, dangane da buƙatun masu siye. Kowane kunshin yana da alama tare da ranar gwaji da ranar samarwa, don tabbatar da sauƙaƙe kulawar ingancin inganci da ayyukan sa ido.

reference:

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  2. Gwajin gwaji da ke kan cutar Alzheimer yana nuna tasirin tsufa ”(Sanarwar latsawa) Cibiyar Salk. 12 Nuwamba 2015. An dawo da Nuwamba 13, 2015.
  3. Masu bincike sun gano manufar kwayoyin J147, wacce ke dab da gwajin asibiti don magance cutar mantuwa ”. An dawo da 2018-01-30.
  4. Daidaitawar cututtukan Alzheimer Cutar Neuropathologic Canje-canje Tare da Halin Hankali: Nazarin Litattafai Peter T. Nelson, Irina Alafuzoff, Eileen H. Bigio, Constantin Bouras, Heiko Braak, Nigel J. Cairns, Rudolph J. Castellani, Barbara J. Crain, Peter Davies, Kelly Del Tredici, Charles Duyckaerts, Matthew P. Frosch, Vahram Haroutunian, Patrick R. Hof, Christine M. Hulette, Bradley T. Hyman, Takeshi Iwatsubo, Kurt A. Jellinger, Gregory A. Jicha, Enikö Kövari, Walter A Kukull, James B. Leverenz, Seth Love, Ian R. Mackenzie, David M. Mann, Eliezer Masliah, Ann C. McKee, Thomas J. Montine, John C. Morris, Julie A. Schneider, Joshua A. Sonnen, Dietmar R. Thal, John Q. Trojanowski, Juan C. Troncoso, Thomas Wisniewski, Randall L. Woltjer, Thomas G. Beach J Neuropathol Exp Neurol. Rubutun marubuci; akwai a PMC 2013 Jan 30. An buga shi a cikin ingantaccen tsari na ƙarshe kamar: J Neuropathol Exp Neurol. 2012 Mayu; 71 (5): 362-381. Doi: 10.1097 / NEN.0b013e31825018f7

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