Vinpocetine

Vinpocetine foda 42971-09-5 Bayanan Basan

sunan	Vinpocetine
CAS	42971-09-5
tsarki	98%
Chemical name	maganin vinpocetine
nufin abu ɗaya ne	AY-27255, Cavinton, Eburnamenine-14-carboxylic acid, Ethyl Apovincaminate, Ethylapovincaminoate, Ethyl Ester, RGH-4405, TCV-3b, Vinpocetin, Vinpocetina, Vinpocétine.
kwayoyin Formula	C22H26N2O2
kwayoyin Weight	350.5 g / mol
Ƙaddamarwa Point	/
InChI Key	DDNCQMVWWZOMLN-IRLDBZIGSA-N
Form	foda
Appearance	White
Rabin Rayuwa	2 zuwa 4 hours
solubility	/
Storage Yanayin	Adana a zazzabi a daki, a cikin akwati na iska na iska, kiyaye iska, kariya daga zafi, haske da zafi.
Aikace-aikace	Ana amfani da Vinpocetine don haɓaka ƙwaƙwalwa da haɓaka ƙwaƙwalwar kwakwalwa. Hakanan an yi amfani dashi don ischemia da raunin sake farfadowa, kuma ana ɗaukarsa wakili ne mai kare lafiyar jiki. Koyaya, akwai fewan ingantattun karatun asibiti don tallafawa amfani da vinpocetine a bugun jini, rashin hankali, ko wasu cututtukan CNS.
Takardar Gwaji	Ya Rasu

 

Vinpocetine foda 42971-09-5 Janar Bayani

Vinpocetine foda shine kayan haɗin roba wanda aka samo daga vincamine, wani abu da aka samo a cikin ganyayyaki na ƙananan tsire-tsire na periwinkle (ƙananan Vinca) Vinpocetine an haɓaka shi a ƙarshen shekarun 1960 kuma ana samun sa azaman likitancin magani a Turai da Japan ƙarƙashin sunayen sunaye Cavinton, Cavinton Forte, Intelectol, da sauransu.

Ana amfani da Vinpocetine don haɓaka ƙwaƙwalwa da haɓaka ƙwaƙwalwar kwakwalwa. Hakanan an yi amfani dashi don ischemia da raunin sake farfadowa, kuma ana ɗaukarsa wakili ne mai kare lafiyar jiki. Koyaya, akwai fewan ingantattun karatun asibiti don tallafawa amfani da vinpocetine a bugun jini, rashin hankali, ko wasu cututtukan CNS.

 

Vinpocetine foda 42971-09-5 Tarihi

Vinpocetine an fara hada shi a karshen 1960s daga vincamine kuma an siyar dashi a karkashin sunayen kasuwanci, kamar Cavinton da Intelectol, tun a ƙarshen 1970s. Vinpocetine an inganta shi sosai don amfani a cikin cututtukan kwakwalwa na asalin jijiyoyin jini, yayin da V. ƙarami yana da yawa da yawa, amfani da gargajiya ciki har da laxative, antilactaogogue, da emmenagogue.

 

Vinpocetine foda 42971-09-5 Mechanism Of Action

Hanyoyin vinpocetine foda suna da yawa. Ya bayyana yana hulɗa tare da tashoshin ion da yawa (sodium, potassium, da calcium) yayin da yake haifar da sakamako mai tasiri a kan sakin neurotransmitter da neuroprotection lokacin da aka hana dopamine ko glutamate (waɗannan biyun, lokacin da gubobi ba tare da buƙata ba, na iya haifar da lalacewar abu mai guba). Hakanan yana hulɗa tare da masu karɓar adrenergic na alpha da mai karɓar TPSO, kuma yayin da ainihin amfanin waɗannan hulɗar masu karɓar ba bayyananniya bane wataƙila sun dace ne tunda sun faru ne a daidai irin abubuwan da hulɗar tashar tashar ion ke yi.

Vinpocetine ma mai hana PDE1 ne, wanda shine hanyar da ke da ƙarfin zuciya da haɓaka haɓaka. Abun takaici, wannan hanawa yana faruwa a madaidaicin kashi kuma bazai iya amfani da daidaitattun ƙwayoyin maganin vinpocetine ba.

Hakazalika da PDE1, yiwuwar maganin vinpocetine da hana kai tsaye ga masu karɓa masu yaduwar cutar duka suna faruwa ne a cikin ƙananan ƙwayoyin cuta a cikin vitro kuma bazai dace da daidaitaccen ƙarin ba.

 

Vinpocetine foda 42971-09-5 Aikace-aikace

Inganta alamomin cutar mantuwa

Vinpocetine da farko ya sami sanarwa saboda an ce yana kara yawan jini zuwa kwakwalwa, sakamakon da wasu suka yi imanin na iya inganta alamun cutar Alzheimer.

Rage Kiba

Wasu kuma sun sanya shi da kayan aikin thermogenic, suna ba da shawarar cewa zai iya “ƙona kitse” ko haɓaka aikin motsa jiki.

An ga sakamako yayin tantance vinpocetine azaman asarar nauyi ko ƙarin wasanni.

Wani binciken da aka buga a shekarar 2016, wanda aka gudanar a Jami'ar Kudancin Florida a shekarar 2016, ya ba da rahoton cewa karin mai mai dauke da sinadarin vinpocetine yana kara karfin sinadarin hutawa (RMR) a cikin 'yan wasa maza 10 amma bai yi komai ba don rage kitsensu.

 

Vinpocetine foda 42971-09-5 researcharin bincike

Lokacin da aka ɗauke ta baki: Vinpocetine shine Zai yiwu SAFE ga mafi yawan mutane lokacin da aka ɗauke ta bakin da kyau, gajere. Vinpocetine na iya haifar da wasu lahani ciki har da ciwon ciki, tashin zuciya, tashin hankali na bacci, ciwon kai, jiri, tashin hankali, da zubar fuska.

 

Vinpocetine foda 42971-09-5 Magana

[1] Cohen, Pieter A. (Oktoba 2015). "Vinpocetine: An Drugayar da Drugwayar da ba a Amince da ita ba a matsayin plementarin Abinci" Ayyukan Mayo Clinic. 90 (10): 1455. doi: 10.1016 / j.mayocp.2015.07.008. PMID 26434971.

[2] Shirin Toxicology na Kasa (Satumba 2013). "Takaddun Nazarin Bayanin Kayan Gida don Vinpocetine (CAS No. 42971-09-5)" (PDF). Ma'aikatar Lafiya ta Amurka da Sabis. An dawo da Disamba 28, 2018.

[3] Almada, Bianca (Yuli 6, 2015). "Da'awar karya don karin kwakwalwa ta jawo dala 152 daga FTC". Rijistar Yankin Orange. An dawo da Janairu 1, 2019.

[4] Myers, Steve (Yuli 8, 2015). "Memarin Markan kasuwar Memory ya sasanta lamarin FTC akan $ 150M". Kayan Kayan Gida na Halitta. An dawo da 1 Janairu 2019.