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N-AcetylneuraminiC ACID (SIALIC ACID) 131-48-6

N-AcetylneuraminiC ACID (Sialic acids) dangi ne na monosaccharides tara-carbon acid wanda ke faruwa a ɗabi'a a ƙarshen sarƙoƙin sukari haɗe da saman ƙwayoyin da sunadarai masu narkewa. A cikin jikin mutum, mafi girman kwayar sialic acid (as N-acetylneuraminic acid) yana faruwa a cikin kwakwalwa inda take shiga a matsayin wani ɓangare na ɓangaren tsarin ganglioside a cikin synaptogenesis da watsawar jijiyoyi.

Kirkira: Production Batch
Package: 1KG / jaka, 25KG / drum
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N-AcetylneuraminiC ACID (SIALIC ACID) 131-48-6 Bayanan Basan

sunan N-AcetylneuraminiC ACID (SIALIC ACID)
CAS 131-48-6
tsarki 98%
Chemical name N-Acetylneuraminic ACID
nufin abu ɗaya ne Neuraminic acid
kwayoyin Formula C11H19NO9
kwayoyin Weight 309.27 g / mol
Ƙaddamarwa Point 185 ℃
InChI Key SQVRNKJHWKZAKO-UHFFFAOYSA-N
Form foda
Appearance White foda foda
Rabin Rayuwa /
solubility /
Storage Yanayin Adana a zazzabi a daki, a cikin akwati na iska na iska, kiyaye iska, kariya daga zafi, haske da zafi.
Aikace-aikace Anti-tsufa supplement karin abincin
Takardar Gwaji Ya Rasu

 

N-AcetylneuraminiC ACID (SIALIC ACID) 131-48-6 Janar Description

Sialic acid kalma ce ta gama gari ga dangin sunadarai na neuraminic acid, sukari mai guba tare da kashin kashin tara.Haka kuma suna ne ga mafi yawan membobin wannan rukunin, N-acetylneuraminic acid (Neu5Ac ko NANA).

 

N-AcetylneuraminiC ACID (SIALIC ACID) 131-48-6 Tarihi

N-AcetylneuraminiC ACID Sialic acid ana samunsu yadu a yadu cikin kayan dabbobi da kuma karami a wasu kwayoyin, tun daga fungi zuwa yeast da kwayoyin cuta, galibi a cikin glycoproteins da gangliosides (suna faruwa ne a ƙarshen sarkar sukari da aka haɗa da saman ƙwayoyin da kuma sunadarai masu narkewa). Wancan ne saboda da alama ta bayyana ne a ƙarshen juyin halitta. [Faɗar da ake buƙata] Koyaya, an lura da shi a cikin amosanin amo na Drosophila da sauran kwari da kuma cikin kwayar polysaccharides na wasu ƙwayoyin cuta. Gabaɗaya, tsire-tsire basu ƙunshi ko nuna sialic acid.

 

N-AcetylneuraminiC ACID (SIALIC ACID) 131-48-6 Mechanism OAction

A cikin mutane kwakwalwa tana da mafi girman girman sialic acid, inda waɗannan acid ɗin ke taka muhimmiyar rawa wajen watsa jijiyoyin jiki da tsarin ganglioside a cikin synaptogenesis. Fiye da nau'ikan sialic acid 50 sanannu ne, duk ana iya samun su daga kwayar neuraminic acid ta maye gurbin amino group na ɗayan rukunin hydroxil ɗin sa. Gabaɗaya, ƙungiyar amino tana ɗaukar ko dai acetyl ko ƙungiyar glycolyl, amma an bayyana wasu canje-canje. Waɗannan gyare-gyaren tare da alaƙa sun nuna cewa takamaiman nama ne da kuma maganganun ci gaba, saboda haka wasu daga cikinsu ana samun su ne kawai a kan wasu nau'ikan glycoconjugates a cikin takamaiman ƙwayoyin halitta. [3] Masu maye gurbin hydroxyl na iya bambanta da yawa; acetyl, lactyl, methyl, sulfate, da phosphate kungiyoyin an samo.

 

N-AcetylneuraminiC ACID (SIALIC ACID) 131-48-6 Aikace-aikace

  1. "Zinariyar kwakwalwa" na ci gaban ilimi

A cikin dabbobi masu shayarwa, hanta ne ke hada N-AcetylneuraminiC ACID (SIALIC ACID). Yana da mahimmanci na gina jiki a cikin nono, wanda zai iya inganta ci gaban kwakwalwa da jijiyoyin jijiyoyi a jarirai da yara ƙanana, inganta ƙwaƙwalwa da hankali, inganta rigakafin jarirai da uwaye;

  1. Detox antibacterial, inganta rigakafin jiki.

 N-AcetylneuraminiC ACID (SIALIC ACID) ba wulakanta shi ta hanyar enzymes a cikin hanyar narkewa ba, yana samar da glycoproteins wanda ke toshe abin da ke rataya da kwayoyin cuta (ƙwayoyin cuta, ƙwayoyin cuta da guba na ƙwayoyin cuta) ga ƙwayoyin endocrin, kuma zai iya inganta gano kwayar halitta, ta lalata sinadarin kwalera hana kamuwa da cuta daga cutar E. coli, daidaita rabin rayuwar sunadaran jini, don haka inganta ingantaccen aikin garkuwar mutum. A lokaci guda, N-AcetylneuraminiC ACID (SIALIC ACID) na iya inganta shayarwar cikin bitamin da kuma ma’adanai. Inganta rigakafin jariri da uwa; N-AcetylneuraminiC ACID (SIALIC ACID) ita ma kanta tana ba da gudummawa ga tasirin haihuwa mai ɗorewa, tana taimaka wa mata masu ciki don haihuwa cikin ƙoshin lafiya, kuma yana hanzarta murmurewar bayan fage

  1. Jinkirta tsufa da tsawaita rayuwa.

 Fuskar kwayoyin jikin mutum yana da kauri mai kauri na N-AcetylneuraminiC ACID (SIALIC ACID), yana daidaita rayuwar kwayar halitta da sadarwar bayanan kwayar halitta, rashi N-AcetylneuraminiC ACID (SIALIC ACID) na iya haifar da rayuwa da kwayar halittar rayuwa da kuma sunadarin enzyme. Kuma N-AcetylneuraminiC ACID (SIALIC ACID) na iya inganta nitsarwar N-AcetylneuraminiC ACID (SIALIC ACID) a cikin jiki, hana zubar kwayar halittar N-AcetylneuraminiC ACID (SIALIC ACID), jinkirta tsufa, yana da rawar tsawon rai .

 

N-AcetylneuraminiC ACID (SIALIC ACID) 131-48-6 researcharin bincike

Glycoproteins mai cike da sinadarin siialic acid (sialoglycoproteins) sunada zabi a cikin mutane da sauran kwayoyin. Kwayoyin kansar metastatic galibi suna bayyana babban adadin sicoic acid mai arzikin glycoproteins. Wannan wuce gona da iri na sialic acid akan saman yana haifar da caji mara kyau akan membranes ɗin salula. Wannan yana haifar da ƙyama tsakanin ƙwayoyin halitta (sel adawa) kuma yana taimaka wa waɗannan ƙwayoyin cutar kanjamau su shiga rafin jini. Gwaje-gwajen da aka yi kwanan nan sun nuna kasancewar sialic acid a cikin matrix mai ɓoye ƙananan ƙwayoyin cuta.

 

N-AcetylneuraminiC ACID (SIALIC ACID) 131-48-6 Bayani

[1] Severi E .; Hood DW; Thomas GH (2007). "Amfani da Sialic acid ta hanyar cututtukan ƙwayoyin cuta". Ilimin halittu kanana. 153 (9): 2817-2822. Doi: 10.1099 / mic.0.2007 / 009480-0. PMID 17768226

[2] Schauer R. (2000). "Nasarori da ƙalubalen binciken sialic acid". Glycoconj. J. 17 (7-9): 485–499. Doi: 10.1023 / A: 1011062223612. PMC 7087979. PMID 11421344

[3] Racaniello, Vincent (5 Mayu 2009). "Haɗa ƙwayoyin cutar mura a cikin ƙwayoyin halitta: rawar ƙwayoyin sialic acid daban-daban". Blog na Virology. An dawo da 10 Afrilu 2019.

[4] Warren, Leonard; Felsenfeld, Herbert (1962). "Biosynthesis na Sialic Acids" (PDF). Jaridar ilmin sunadarai. 237 (5): 1421.

 

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