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Anandamide (AEA) foda (94421-68-8)

Anandamide foda wani lamari ne mai faruwa wanda ke faruwa a cikin kwakwalwa, wanda ke nufin cewa kwakwalwar dan adam zata iya samarda anandamide ba tare da cin abinci mai dauke da AEA ba. An tabbatar da kwakwalwar halittun dabbobi masu shayarwa da kuma cacao mai daɗi sun ƙunshi adadin anandamide.

Kirkira: Production Batch
Package: 1KG / jaka, 25KG / drum
Wisepowder yana da ikon samarwa da samar da adadi mai yawa. Duk samarwa a ƙarƙashin yanayin cGMP da tsarin kula da ingancin inganci, duk takaddun gwaji da samfurin akwai.
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Anandamide (AEA) foda (94421-68-8) bidiyo

 

 

Bayanin Bishiyar Anandamide (AEA)

sunan Anandamide (AEA) foda
CAS 94421-68-8
tsarki 98%
Chemical name N-(2-Hydroxyethyl)-5Z,8Z,11Z,14Z-eicosatetraenamide
nufin abu ɗaya ne Arachidonoyl Ethanolamide, AEA, arachidonoylethanolamide, (5Z, 8Z, 11Z, 14Z) -N- (2-hydroxyethyl) icosa-5,8,11,14-tetraenamide, N-arachidonoylethanolamine
kwayoyin Formula C22H37NO2
kwayoyin Weight 347.53
Ƙaddamarwa Point /
InChI Key LGEQQWMQCRIYKG-DOFZRALJSA-N
Form mai
Appearance Rawaya mai haske
Rabin Rayuwa /
solubility Mai narkewa a cikin DMSO (~ 30 mg / ml), DMF (~ 10 mg / ml), ethanol mai ruwa (5 mg / ml), PBS, pH 7.2 (~ 100 mg / ml), da ruwa (<0.1 mg / ml at 25 ° C).
Storage Yanayin 80 ° C (des.)
Aikace-aikace Oan wasan cannabinoid mai ɗaukar ligand
Takardar Gwaji Ya Rasu

 

Bayanin Janar na Anandamide (AEA)

Anandamide, wanda aka fi sani da N-arachidonoylethanolamine (AEA), mai karɓar ƙwayoyin cuta ne wanda ya samo asali daga haɓakar haɓakar eidosatetraenoic acid (arachidonic acid), muhimmin omega-6 fatty acid. An ɗauke sunan daga kalmar Sanskrit ananda, wanda ke nufin "farin ciki, ni'ima, ni'ima", da amide. An hada shi daga N-arachidonoyl phosphatidylethanolamine ta hanyoyi da yawa.

Bayan ƙarancin kirkirar, anandamide yana da fa'idodi masu yawa, anan shine babban bayanin su.

Memorywaƙwalwar Aiki - Wannan yana daga cikin mahimmin kayan aikin kerawa. Kamar yadda aka ambata a sama, anandamide yana taimakawa tara bayanai da yawa domin ƙirƙirar sabbin dabaru. Akwai karancin karatu a kan manya masu lafiya, amma samfurin guda daya ya nuna cewa berayen da ke fama da raunin ƙwaƙwalwar aiki sun inganta wannan ma'aunin tare da anandamide kawai.

Daga wannan tabbacin, a bayyane anandamide ke hulɗa tare da ƙwaƙwalwar aiki tare da kayan aiki da yawa. An tabbatar da canji a kimiyance, amma ga lafiyayyun tsofaffi har yanzu ba'a san girmansa ba.

Neurogenesis - A cewar Dokta Gary Wenk, anandamide na iya zama mai guba mai ƙarfi da ke da alaƙa da neurogenesis musamman ma a cikin tsofaffi. A matsayinsa na mai binciken neuroscience, yana da fahimta kan tasirin anandamide da hulda da kwakwalwa.

Har zuwa kwanan nan, masana kimiyya sun yi imani da cewa neurogenesis (girma na sababbin ƙwayoyin kwakwalwa) ya faru ne kawai a cikin matasa da matasa. A yau sanannu ne cewa neurogenesis yana ci gaba da zama cikin girma kuma mafi kyawu zamu iya sarrafa shi, ƙarancin haɗarin da muke da shi na matsalolin neurodegenerative kamar batutuwan ƙwaƙwalwa da dementia.

Anti-Damuwa - Bayan amfanin fahimi, akwai yanayi da yawa da haɓaka rayuwa tare da anandamide. Nazarin nau'ikan ƙirar kwakwalwar bera suna ba da shawarar anandamide yana da tasiri mai ƙarfi na lalata damuwa a cikin kwakwalwa, wanda zai iya taimakawa waɗanda ke da mummunan yanayi.

 

Anandamide (AEA) foda (94421-68-8) Tarihi

Anandamide an fara bayyana (kuma mai suna) a cikin 1992 ta Raphael Mechoulam da membobin kamfanin WA Devane da Lumír Hanuš.

 

Anandamide (AEA) Aikace-aikacen foda

Anandamide yana haɓaka enzymatically a cikin sassan kwakwalwa waɗanda ke da mahimmanci a ƙwaƙwalwar ajiya, tunani da sarrafa motsi. Bincike ya nuna cewa anandamide yana taka rawa wajen ƙirƙirar haɗin gwaiwa na gajere tsakanin ƙwayoyin jijiya, kuma wannan yana da alaƙa da koyo da ƙwaƙwalwa. Nazarin dabbobi sun nuna cewa yawan ƙwayar anandamide yana haifar da mantawa. Wannan yana nuna cewa idan har za'a iya samarda abubuwa wadanda zasu hana anandamide su daure wa mai karbarsa, to wadannan ana iya amfani dasu don magance asarar ƙwaƙwalwar ajiya ko don inganta ƙwaƙwalwar data kasance!

 

Anandamide (AEA) researcharin bincike

Black barkono ya ƙunshi alkaloid guineesine, wanda shine mai hana anandamide reuptake. Saboda haka yana iya ƙara tasirin ilimin anandamide.

Dosearancin shan anandamide yana da tasirin tashin hankali, amma yawan cin abinci a cikin beraye yana nuna mutuwar hippocampus.

Wata mata 'yar Scotland wacce ba kasafai ake samun hadarin kwayar halitta ba a cikin kwayar ta FAAH tare da haifar da girman yanayin anandamide an sami rahoton cutarwa daga damuwa, ta kasa fuskantar tsoro da kuma matsananciyar wahala. Yawan konewa da yankan da take fama dashi sakamakon yawan haihuwar jikinta ya warke da sauri.

 

Anandamide (AEA) foda (94421-68-8) Tunani

  • Devane, W; Hanus, L; Breuer, A; Pertwee, R.; Stevenson, L.; Griffin, G; Gibson, D; Mandelbaum, A; Etinger, A; Mechoulam, R (18 Disamba 1992). "Keɓewa da tsarin tsarin kwakwalwa wanda ke ɗaura ga mai karɓar Cannabinoid". Kimiyya. 258 (5090): 1946–
  • Mechoulam R, Fride E (1995). "Hanyar da ba a san ta ba zuwa ga kwayar cutar Cannabinoid ligands, anandamides". A cikin Pertwee RG (ed.). Cannabinoid masu karɓa. Boston: Cibiyar Nazarin Ilimi. shafi na 233–
  • Battista, N., da Maccarrone, M. (2017). “Tsarin aikin asali na kwayar halitta da kuma babban aikin endocannabinoids,” a cikin Tsarin Endocannabinoid: Genetics, Biochemistry, Rashin Lafiya na Brain, da kuma Therapy, ed. E. Murillo-Rodriguez (Amsterdam: Elsevier), 1-24.
  • Devane et al. (1992), Kebancewa da tsarin tsarin kwakwalwa wanda ke daure ga mai karba na cannabinoid; Kimiyya, 258 1946.
  • Anandamide (AEA): Duk Abinda Yakamata Ku San Shi

 

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