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Lycopene 10% (502-65-8)

Lycopene carotenoid ne da aka samo a cikin 'ya'yan itatuwa da kayan marmari da yawa kamar kankana, guava ruwan hoda, da tumatir. Lycopene wani sinadari ne mai kariya na kariya. Ana ba da shawarar cewa tsirrai ke amfani da shi don kiyaye shi daga nau'in oxygen mai sawa (ROS). Lycopene muhimmin memba ne na iyalai na carotinoid. Kamar yadda antioxidant mai ƙarfi, fiye da bitamin-E sau ɗari da fiye da b-carotene sau biyu, Antioxidant musamman ya sami kulawa sosai daga masu bincike a cikin 'yan shekarun nan.

Kirkira: Production Batch
Package: 1KG / jaka, 25KG / drum
Wisepowder yana da ikon samarwa da samar da adadi mai yawa. Duk samarwa a ƙarƙashin yanayin cGMP da tsarin kula da ingancin inganci, duk takaddun gwaji da samfurin akwai.
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Lycopene (502-65-8) bidiyo

 

Bayanin Lantarki na Lycopene

sunan Lycopene
CAS 502-65-8
tsarki 10%
Chemical name lycopene
nufin abu ɗaya ne LYCOPENE, ci 75125

psi-carotene

ci 75125 ku

kwayoyin Formula C40H56
kwayoyin Weight 536.87
Ƙaddamarwa Point 174.00 zuwa 175.00 ° C. @ 760.00 mm Hg
InChI Key OAIJSZIZWZSQBC-GYZMGTAESA-N
Form foda
Appearance jan lu'ulu'u mai haske
Rabin Rayuwa /
solubility THF: 1 mg / mL

chloroform: 5 mg / mL

Storage Yanayin Adana a cikin sanyi, bushe da duhu daga nesa, zafi da oxygen. Da zarar an buɗe, yi amfani da shi da wuri-wuri.
Aikace-aikace Anti-tsufa da anti-alagammana creams, lotions, mala'iku, rana kula & kayan shafa.
Takardar Gwaji Ya Rasu

 

Bayanin Janar Lycopene

Lycopene sinadarai ne na yanayi wanda ke ba 'ya'yan itatuwa da kayan marmari jan launi. Yana daya daga cikin yawan launukan da ake kira carotenoids. Ana samun Lycopene a cikin kankana, ruwan inabi masu ruwan hoda, apricots, da ruwan guavas mai ruwan hoda. Ana samun sa musamman a cikin tumatir da kayayyakin tumatir. A arewacin Amurka, kashi 85% na sinadarin lycopene yana zuwa ne daga kayan tumatir kamar ruwan tumatir ko manna. Kofi ɗaya (ruwan sha 240) na ruwan tumatir yana ba da kusan 23 mg na lycopene. Sarrafa ɗanyen tumatir ta hanyar amfani da zafin rana (wajen yin ruwan tumatir, tumatir ko kuma ketchup, alal misali) a zahiri yana canza sinadarin lycopene a cikin ɗanyen samfurin zuwa hanyar da ta fi sauƙi ga jiki amfani da shi. Lycopene a cikin kari yana da sauƙin amfani da jiki azaman lycopene da ake samu a cikin abinci. Mutane Suna shan lycopene don hana cututtukan zuciya, "taurarewar jijiyoyi" (atherosclerosis); da ciwon daji na prostate, nono, huhu, mafitsara, ovaries, maza, da kuma pancreas. Hakanan ana amfani da Lycopene don magance kamuwa da cutar papilloma virus (hpv), wanda shine babban dalilin kansar mahaifa. Wasu mutane kuma suna amfani da lycopene don cutar ido da asma.

 

Lycopene (502-65-8) Tarihi

Lycopene wani nau'in tetraterpene ne mai daidaituwa tare daga sassan takwas Shi memba ne na dangin carotenoid, kuma saboda yana kunshe da carbon da hydrogen, shima carotene ne. Hanyoyin keɓewa na lycopene an fara bayar da rahoton a cikin 1910, kuma tsarin kwayoyin yana da ƙaddara ta 1931 A dabi'ance ta, duka-trans form, kwayoyin suna da tsayi kuma madaidaiciya, tsarinsa na 11 ya daidaita biyu. Kowane fadada a cikin wannan tsarin yana rage kuzarin da ake buƙata don wayoyin lantarki su canza zuwa jihohin da suke da ƙarfi, yana bawa kwayoyin damar karɓar hasken bayyane na tsawan lokaci mai tsawo. Lycopene yana ɗaukar abu duka amma mafi tsayin zango na haske wanda ake iya gani, don haka ya bayyana da ja.

 

Tsarin Hannu na Lycopene

Ayyukan Antioxidant

An gane damuwa mai mahimmanci a matsayin ɗayan manyan masu ba da gudummawa ga haɗarin haɗarin cututtukan zuciya da jijiyoyin jini. Daga cikin carotenoids na yau da kullun lycopene yana tsaye a matsayin mafi ƙarfin antioxidant kamar yadda aka nuna ta tsarin gwajin in vitro.1 Dangane da wannan binciken ana iya tsara ƙarfin antioxidant na carotenoids kamar haka: lycopene> [ya fi] alpha-tocopherol> alpha-carotene> beta-cryptoxanthin> zeaxanthin> beta-carotene> lutein. Haɗin carotenoids sun fi tasiri fiye da mahaɗa ɗaya.19 Wannan tasirin aikin haɗin gwiwar an fi bayyana shi lokacin da lycopene ko lutein suke. Babban kariya daga cakuda na iya kasancewa yana da alaƙa da takamaiman matsayi na carotenoids daban-daban a cikin ƙwayoyin ƙwayoyin halitta.

Yawancin karatu na amfani da tumatir suna nuna kaddarorin antioxidant a cikin mutane. Misali, kwanannan an gano cewa amfani da kayan tumatir na yau da kullun wanda ke dauke da 15 mg lycopene tare da sauran magungunan tumatir na haɓaka mahimmancin kariya daga ƙwayoyin lipoproteins daga wahalar rashin ƙarfi na oxidative.43 Waɗannan sakamakon sun nuna cewa ƙwayoyin lycopene da aka ɗora daga kayan tumatir na iya yin aiki a cikin vivo maganin antioxidant.

 

Hibarfin cutar kansa da ke yaɗuwa (hawan sel)

An gano cewa Lycopene yana hana yaduwar nau'ikan kwayoyin cutar kansa da suka hada da na nono, da na huhu, huhu, da kuma endometrium. Sakamakon hanawa na lycopene akan mammary da ciwan kansa na prostate ba su da apoptotic (wanda aka shirya) ko necrotic (sakamakon rauni ko cuta) mutuwar ƙwayar cuta, wata hanyar da ta shafi aikin wasu kwayoyi amma ba don abubuwan haɓaka jiki ba koyaushe suna cinye mutum. abinci. Wannan sakamako yana haɗuwa tare da hana ci gaban zagayowar sel daga G0 / G1 zuwa S S kamar yadda aka auna ta hanyar cytometry.3 inarfin haɓakar sel yana haɗuwa tare da raguwa a cikin matakan furotin na D1 cyclin wanda shine babban mahimmin tsari na wannan aikin. Sanannen abu ne cewa abubuwan haɓaka suna da tasiri akan yanayin sake zagayowar tantanin halitta (da farko yayin tafiyar G1) kuma cewa manyan abubuwanda suke aiki azaman na'urori masu auna sigina shine nau'ikan cyclins.44 Bugu da ƙari, cyclin D1 sanannu ne azaman aikin oncogene (gene) wanda dysregulation ke haifar da sel na yau da kullun su zama masu cutar kansa) kuma an gano ana iya bayyana shi a cikin lamuran ƙwayoyin nono da yawa da kuma a cikin ciwukan farko.45 Saboda haka, raguwa a cikin ɗakunan hawan jini na D1 ta hanyar lycopene yana ba da cikakken bayani game da aikin maganin cutar ta kansa na carotenoid.

 

Shiga ciki tare da abubuwan haɓakawa na haɓakar ƙwayar cutar daji

Haɓaka haɓakar ƙwayoyin cutar kansa ta hanyar ƙwayar cuta ta insulin-kamar ci gaban insulin 1 (IGF-1) an rage shi da yawa ta hanyar ilimin halittar ilimin halittar jiki na lycopene a cikin gwaji a cikin binciken vitro.2, 46 Muhimmancin wannan binciken don hana rigakafin cutar daji yana da alaƙa da bincike mai karya garkuwar jiki cewa haɓaka matakan IGF-1 yana haɓaka haɗarin rayuwar nono da na kansa a kan mahaifa.47, 48 Idan an tabbatar da tsangwama na tsinkayar ƙwayar ƙwayar cuta ta IGF-1 a cikin nazarin asibiti, wannan zai samar da ingantacciyar ma'ana don bayar da shawarar ƙara yawan ƙwayar lycopene, musamman ta hanyar kayayyakin abinci na tumatir, don rigakafin cutar kansa.

 

Aikace-aikacen Lycopene (502-65-8)

An yi amfani da Lycopene:

a cikin babban aikin ruwa na chromatography (HPLC) don tantance taro a cikin hanta, koda da naman huhu

don jawo urokinase plasminogen mai kunnawa mai kunnawa (uPAR) A cikin layin ƙwayar ciwon daji na prostate

a cikin tsarin fasahar sinadarai na Raman don gano da kuma ganin yadda za'a rarraba shi na ciki

 

Lycopene (502-65-8) researcharin bincike

Wani bita da aka gudanar a shekarar 2017 ya kammala cewa kayayyakin tumatir da kuma karin sinadarin lycopene suna da kananan sakamako masu kyau a kan abubuwan da ke tattare da hadari na zuciya da jijiyoyin jini, kamar hawan jini da jini. Binciken da aka yi a shekara ta 2010 ya nuna cewa bincike bai isa ba don tabbatar da cewa ko amfani da sinadarin lycopene yana shafar lafiyar dan adam.Lycopene an yi nazari a cikin bincike na asali da na asibiti domin illolin da yake da shi a kan cututtukan zuciya da jijiyoyin jini, duk da cewa sakamakon da aka samu ta hanyar 2017 bai canza ra'ayin FDA ba game da hakan shaidar fa'ida har yanzu ba ta cika ba.

 

Tunani Lycopene (502-65-8)

  • Mordente A, Guantario B, Meucci E, Silvestrini A, Lombardi E, Martorana GE, Giardina B, Böhm V. Lycopene da cututtukan zuciya: sabuntawa. Curr Med Chem. 2011; 18 (8): 1146-1163.
  • Devaraj, S., Mathur, S., Basu, A., Aung, HH, Vasu, VT, Meyers, S., da Jialal, I. Nazarin-amsar kashi-kashi game da tasirin tsabtace ɗakunan ƙwayoyin halitta akan haɓakar ƙwayoyin cutar damuwa . J.Am.Coll.Nutr. 2008; 27 (2): 267-273.
  • Cardinault N, Abalain JH, Sairafi B, et al. Lycopene amma ba lutein kuma ba zexanxanthin yana raguwa a cikin ƙwayoyin magani da kuma lipoproteins a cikin marasa lafiya da ke da dangantaka da tsufa na ilimin tsufa. Clin Chim Acta. 2005; 357 (1): 34-42.
  • Mackinnon ES1, Rao AV, Josse RG, Rao LG. Haɓakawa tare da maganin antioxidant lycopene yana rage sigogin damuwa na oxidative da kuma alamar reshepeptide nau'in I collagen a cikin mata na postmenopausal. Osteoporos Int. 2011 Apr; 22 (4): 1091-101.
  • Tasirin Lafiya na Lycopene 丨 Asirin Longevity 2020

 

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