HBT1 foda (489408-02-8)

HBT1 foda (489408-02-8) bidiyo

HBT1 foda (489408-02-8) Bayanin Base

HBT1 foda (489408-02-8) Babban bayanin

HBT1 foda shine mai karɓar mai karɓar AMPA tare da ƙananan tasirin azaba, yana guje wa amsa mai kama da kararrawa a cikin aikin BDNF na vitro. Amfani ne na AMPA-R [alpha-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid (AMPA)] wanda ke haifar da samar da kwayar cutar da ke haifar da kwakwalwa (BDNF) kuma tana nuna tasirin tashin hankali a matakin farko ƙwayoyin cuta HBT1 yana ɗaure ga yankin AMPA-R mai ɗaukar ligand a cikin hanyar dogara da glutamate.

HBT1 foda (489408-02-8) Tunani

[1] Kunugi A, Tajima Y, Kuno H, Sogabe S, Kimura H. HBT1, Novel AMPA Receptor Potentiator with Lower Agonistic Effect, Guji Amsa Kirar Bell a cikin Injin Vitro BDNF. J Pharmacol Mai Magana. 2018 Mar; 364 (3): 377-389. Doi: 10.1124 / jpet.117.245050. Epub 2018 Jan 3. An buga PMID: 29298820.