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HBT1 foda (489408-02-8)

01 Overview

HBT1 foda shine AMPA-R [alpha-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid (AMPA) mai karɓa] mai ƙarfi wanda ke haifar da haifar da ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwayar kwakwalwa (BDNF) kuma yana nuna tasirin agonistic kaɗan na farko neurons. HBT1 yana ɗaure zuwa yanki na haɗin ligand na AMPA-R a cikin yanayin dogara.

yi:  Production Batch
Package:  1KG / jaka, 25KG / drum

02 HBT1 foda (489408-02-8) bidiyo

03 HBT1 foda (489408-02-8) Bayanin Base

 

sunan HBT1 foda
CAS 489408-02-8
tsarki 98%
Chemical name 2-(((5-Methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl)acetyl)amino)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide
nufin abu ɗaya ne HBT1; HBT-1; HBT 1
kwayoyin Formula C16H17F3N4O2S
kwayoyin Weight 386.39
Ƙaddamarwa Point /
InChI Key PHLXSNIEQIKENK-UHFFFAOYSA-N
Form foda
Appearance fararen fata
Rabin Rayuwa /
solubility DMSO: 2 MG / ML, bayyana
Storage Yanayin 0 - 4 C don gajere (kwanaki zuwa makonni), ko -20 C na dogon lokaci (watanni).
Aikace-aikace Amintaccen mai karɓar AMPA
Takardar Gwaji Ya Rasu

04 HBT1 foda (489408-02-8) Babban bayanin

HBT1 foda shine mai karɓar mai karɓar AMPA tare da ƙananan tasirin azaba, yana guje wa amsa mai kama da kararrawa a cikin aikin BDNF na vitro. Amfani ne na AMPA-R [alpha-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid (AMPA)] wanda ke haifar da samar da kwayar cutar da ke haifar da kwakwalwa (BDNF) kuma tana nuna tasirin tashin hankali a matakin farko ƙwayoyin cuta HBT1 yana ɗaure ga yankin AMPA-R mai ɗaukar ligand a cikin hanyar dogara da glutamate.

05 HBT1 foda (489408-02-8) Tarihi

06 HBT1 foda (489408-02-8) Hanyar Neman Aiki

07 HBT1 foda (489408-02-8) Aikace-aikace

08 HBT1 foda (489408-02-8) researcharin bincike

09 HBT1 foda (489408-02-8) Zazzage fayil

COA

10 HBT1 foda (489408-02-8) Tunani

[1] Kunugi A, Tajima Y, Kuno H, Sogabe S, Kimura H. HBT1, Novel AMPA Receptor Potentiator with Lower Agonistic Effect, Guji Amsa Kirar Bell a cikin Injin Vitro BDNF. J Pharmacol Mai Magana. 2018 Mar; 364 (3): 377-389. Doi: 10.1124 / jpet.117.245050. Epub 2018 Jan 3. An buga PMID: 29298820.

 

 

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