Cetilistat foda (282526-98-1)

Cetilistat foda (282526-98-1) bidiyo

Bayanin Cetilistat foda Base

Babban bayanin Cetilistat foda

kiba foda annoba ce ta zamani a ƙasashe masu masana'antu da masu tasowa, kuma a halin yanzu kiba da kiba na haifar da mace -mace a duniya fiye da rashin nauyi. Ceilistat wani labari ne, mai aiki da baki, hanji da kuma hanawar lipase pancreatic. A cikin nazarin in vitro cetilistat ya hana ɗan adam ɗan adam lipase tare da IC50 a cikin ƙaramar nanomolar. A cikin matakan tiyata na asibiti na marasa lafiya masu kiba da marasa lafiya masu kiba tare da nau'in ciwon sukari na 2, cetilistat da aka gudanar tsawon makonni 12 yana rage nauyin jiki sosai, cholesterol low-density lipoprotein (LDL) cholesterol da jimlar cholesterol idan aka kwatanta da placebo. Yawan marasa lafiya masu kiba sun isa raguwa a cikin nauyin jiki na aƙalla 5% ya fi girma a duk makamai masu aiki idan aka kwatanta da placebo. A cikin marasa lafiya masu ciwon sukari masu kiba, matakan glycosylated haemoglobin (HbA1c) suma an rage su da mahimmanci. Ceilistat ya nuna m zuwa matsakaici mara kyau abubuwan da suka faru, galibi na yanayin gastrointestinal (steatorrhea), tare da abin da ke ƙasa da orlistat. An yarda da shi kwanan nan a Japan don maganin kiba tare da rikitarwa.

Cetilistat foda (282526-98-1) Tarihi

Alizyme, ƙwararren kamfanin haɗin gwiwar biopharmaceutical tare da haɗin gwiwar Takeda Pharmaceutical, cetilistat (ATL-962) magani ne na gwaji don kiba. Cetilistat yana hana ƙoshin ƙwayar cututtukan fata da kuma aiki a matsayin wakili don kula da kiba da cututtukan da ke da alaƙa ko dyslipidemia.

Yana haifar da asarar nauyi kuma yana ɗaukar mai daga abinci. Magungunan suna aiki a hankali don rage yawan ci, ba tare da shafi kwakwalwa ba.

A watan Disamba na shekara ta 2008, Takeda ta fara karatun asibiti na Cetilistat a cikin Japan. Ci gaban matakan gwagwarmaya na Mataki na III ya biyo bayan ƙarfafa bayanan gwaji na asibiti na II wanda ya nuna cetilistat yana inganta mahimmancin asarar nauyi kuma an yarda da shi sosai a cikin marasa lafiya na ƙoshin lafiya.

Takeda ta tantance bayanan Turai na cetilistat a watan Agusta na 2003 kuma a cikin Janairu na 2004 sun yi yarjejeniya tare da Alizyme don haɓaka masana'antu da samarwa a cikin Japan.

A watan Oktobar 2012, Takeda ya gabatar da Sabuwar Aikace -aikacen Magunguna (NDA) don Cetilistat ga Ma'aikatar Lafiya, Kwadago da Jin Dadi ta Japan don kula da kiba.

Binciken Alizyme na yanzu da ci gaba yana mayar da hankali kan jiyya don rikicewar ciki, kiba, ciwon daji da ciwon sukari.

Cetilistat (282526-98-1) Hanyar Neman Aiki

Cetilistat maganin hana daukar ciki shine ke hana narkewar kitse da sha, yana haifar da rage karfin jiki, don haka asarar nauyi. Ya banbanta da yawancin sauran masu amfani da ƙwayar kiba kamar yadda baya aiki akan kwakwalwa don rage ci, amma yana aiki sosai. Kwayar ta zauna a cikin ƙwayar gastrointestinal ba tare da wani mahimmancin sha a cikin jiki ba.

Cetilistat (282526-98-1) Aikace-aikace

Cetilistat, a ƙarƙashin sunan alama mai suna Cetislim, Checkwt, ko Kilfat, sabon magani ne wanda a yanzu haka yake fuskantar gwaji da gwaji a ɓangarori daban-daban na duniya don tasirinsa.

An tsara Cetilistat a ƙarƙashin rukunin “anti-kiba ko magungunan anorectic”. Kiba mai yawa yana daga cikin mahimman abubuwan zamani, galibi cikin ƙasashe masu tasowa da masu masana'antu.

Cetilistat magani ne na kwayar cuta mai kiba. Yana da farko yana aiki azaman maganin hana cin abinci na hanji da na jijiyoyin zuciya.

Ana amfani da Cetilistat a matsayin kari ga ingantaccen abinci da motsa jiki na ɗan wani lokaci a cikin maganin kiba. Hakanan ana amfani da Cetilistat don dalilai waɗanda ba a same su a cikin jagorar magunguna ba.

Cetilistat gwaji ne maganin kiba A halin yanzu ana bincikensa a Japan, Amurka, da Turai. Saboda Cetilistat na fuskantar gwaji na asibiti, babu wani inganci ko aminci da aka tabbatar har yanzu ga wannan maganin.

Cetilistat (282526-98-1) Researcharin Bincike

A cikin gwaji na mutane, an nuna cetilistat don haifar da asarar nauyi kamar haka zuwa orlistat, amma kuma ya haifar da sakamako masu illa kamar su mai, barcin kwance, rashin daidaituwa, motsawar hanji na yau da kullun, da rashin ƙarfi. Wataƙila matakan da za a iya amfani da su a wancan sha na mai-mai narkewar bitamin da sauran abubuwan mai-mai narkewa, ana buƙatar amfani da kayan bitamin don hana ƙarancin abinci.

Cetilistat ya gama gwajin Mataki na 1 da na 2 a Yammacin Yamma kuma a halin yanzu yana cikin gwaje-gwaje na Phase 3 a Japan inda ake haɗin gwiwa tare da Takeda. Norgina BV yanzu ya sami cikakken haƙƙin mallaki na duniya game da maganin cetilistat daga Alizyme bayan ƙarshen ya hau mulki.

Gwajin da aka buga na 2 wanda aka buga ya gano cetilistat an rage nauyi tare da shi kuma an sami juriya fiye da orlistat.

Cetilistat (282526-98-1) Tunani

• Yamada Y, Kato T, Ogino H, Ashina S, Kato K: Cetilistat (ATL-962), wani maganin hana daukar ciki mai narkewar motsa jiki, yana motsa jiki kuma yana inganta bayanan martaba na bera. Hanyar Horm 2008 Aug; 40 (8): 539-43. doi: 10.1055 / s-2008-1076699. Epub 2008 Mayu 21.
• Cetilistat don Kula da Kiba: Duk Abubuwan da kuke Bukatar Ku sani

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