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Unifiram (DM232) foda (272786-64-8)

Unifiram foda (sunan lambar haɓakawa DM-232) magani ne na gwaji. wanda ke da maganin rigakafi da sauran tasirin a cikin nazarin dabbobi tare da iko mafi girma fiye da piracetam. Unifiram magani ne mai kama da ampakine wanda aka samo daga biarylpropylsulfonamide, kuma yana da maganin rigakafi da sauran tasirin a cikin nazarin dabbobi tare da har zuwa sau dubu mafi girma fiye da piracetam. Unifiram yana da kaddarorin anti-hypnotic kuma, an nuna shi don rage tsawon lokacin kaddarorin hypnotic na ƙa'idodin barbiturate phenobarbitol ba tare da wani babban tasirin ƙwarewar motsa jiki ba.

Kirkira: Production Batch
Package: 1KG / jaka, 25KG / drum
Wisepowder yana da ikon samarwa da samar da adadi mai yawa. Duk samarwa a ƙarƙashin yanayin cGMP da tsarin kula da ingancin inganci, duk takaddun gwaji da samfurin akwai.
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Unifiram (DM232) foda (272786-64-8) bidiyo

 

Bayanai na Unifiram (DM232) foda Base

sunan Unifiram / DM232 foda
CAS 272786-64-8
tsarki 98%
Chemical name 1- (4-Benzoylpiperazin-1-yl) propan-1-daya
nufin abu ɗaya ne Sunifiram; DM-235; DM 235; DM235;
kwayoyin Formula C14H18N2O2
kwayoyin Weight 246.31
Ƙaddamarwa Point 57-58 ℃
InChI Key DGOWDUFJCINDGI-UHFFFAOYSA-N
Form M foda
Appearance White ko kashe-farin foda
Rabin Rayuwa Rashin sani
solubility Matsala zuwa 5 MM a cikin Ethanol, Mai narkewa cikin ruwa.
Storage Yanayin Store a dakin da zafin jiki ko mai sanyaya, a cikin akwati mai kwalliya wanda aka kulle, an kiyaye shi daga zafi, haske da zafi.
Aikace-aikace DM232 (unifiram) shine mai AMPAkine-kamar nootropic umarni uku na girman ƙarfi fiye da piracetam a cikin nazarin dabbobi.
Takardar Gwaji Ya Rasu

 

Unifiram (DM232) Janar Description

Unifiram wani sabon magani ne wanda zai iya zama ɗayan abubuwan da suka fi ƙarfin ƙwaƙwalwar ƙwaƙwalwa a koyaushe.

Dangane da wata kasida a cikin Binciken Ci gaban Magunguna, wannan rukunin yana alfahari da ƙarfin kusan sau 1,000 fiye da na yanzu nootropics kamar Piracetam da Aniracetam.

Bincike ya nuna cewa Unifiram yana da tasirin gaske a ayyukan ƙwaƙwalwar ƙwaƙwalwa da waɗanda suka yi kama da waɗanda aka fi sani da Racetams.

Unifiram yana da alaƙa da Sunifiram kuma yana aiki a matakin kwakwalwa na ƙari iri ɗaya na girman sashi. Saboda iyakancewar Unifiram mai yawan gaske, yawancin mutane zasu dauki Sunifiram a matsayin wanda ya dace don sauya wannan fili mai tsada.

 

Unifiram (DM232) Tarihin foda

Unifiram (CAS # 272786-64-8) wani abu ne wanda aka ba da rahoto a cikin shekara ta 2000 don samun halaye masu kama da piracetam amma ya fi ƙarfin a cikin gwajin gujewa linzamin kwamfuta. Unifiram (sunan lambar ci gaba DM-232) magani ne na gwaji. wannan yana da maganin rigakafi da sauran sakamako a cikin karatun dabba tare da mafi girman ƙarfi fiye da piracetam. Yawancin sanannun mahadi an san su, kamar sunifiram (DM-235) da sapunifiram (MN-19). [4] [5] [6] Unifiram yana da enantiomers guda biyu, tare da nau'in dextro shine mafi isomer mai aiki. An nuna shi don rage tsawon lokacin hypnosis da pentobarbital ya haifar, ba tare da ɓata haɗin motar ba. Ya zuwa na 2015, ba a gudanar da karatun ɗan adam na yau da kullun tare da inifam ba.

A shekara ta 2006, masu bincike sun yi nazarin halayen magunguna na Sunifiram da Unifiram, inda suka gano cewa waɗannan ɗayan biyun umarni ne na girman girma huɗu fiye da Pircatem. Unifiram, sun gano, yana da ikon hana amnesia ta hanyar daidaituwa da tsarin neurotransmitter da yawa.

 

Unifiram (DM232) Hanyar Neman Aiki

Unifiram shine ingantaccen tsarin gyaran allo na masu karɓa na AMPA. A matsayin Ampakine, Unifiram yana haifar da tasirin glutamate a cikin kwakwalwa wanda ke haifar da mafi kyawun yaduwar synaptic tsakanin ƙwayoyin cuta.

Har ila yau, Unifiram yana kara samar da aikin acetylcholine don samar da ingancin aikinsa kamar Noopept, Pramiraceta, Oxiracetam da sauran racetam nootropics.

An samu bincike kadan a cikin Unifiram fiye da takwaransa Sunifiram, amma waɗannan sunadarai guda biyu suna da alaka da juna kuma sunyi imani suyi aiki a hanyoyi masu yawa.

Sakamakon bincike game da kunnawa na AMPA-receptor wanda ke da alaƙa da tasirin maganin unifiram ya ba da shawara, cewa Unifiram yana aiki azaman mai haɓaka cognition ta hanyar kunna tsarin hana ƙwaƙwalwar ƙwaƙwalwa na AMPA. Wannan fili, kodayake baya nuna kusanci a cikin binciken dauri don mahimman masu karɓar tsakiya ko tashoshi, sun sami damar hana amnesia ta hanyar sauye-sauye na tsarin neurotransmission da yawa kuma yana iya haɓakar sakin acetylcholine daga cortex cortex, aƙalla a cikin binciken akan berayen. .

 

Aikace-aikacen Unifiram (DM232)

DM232 (unifiram) ita ce AMPAkine-kamar nootropic umarni uku na girma fiye da piracetam a karatun dabbobi.

A cikin bincike, an lura cewa unifiram yana da manyan fa'idodi masu zuwa; anti-rigakafi da anti-hypnotic effects, anti-amnesia da acetylcholine agonism. A cikin binciken guda ɗaya, an gano cewa unifiram na iya rage tasirin barbiturates waɗanda ke haifar da rashin daidaituwa da tashin hankali. Tunda acetylcholine yana da alaƙa da haɓaka ƙwaƙwalwar ajiya da koyo, unifiram na iya, don haka, ya kasance da amfani ga ci gaban kwakwalwa.

 

Unifiram (DM232) Researcharin Bincike

Unifiram magani ne a cikin dangin racetam. Tsarinta kamar ampakine ne, kuma tana da kusanci da Sunifiram. Unifiram yana daya daga cikin abubuwan karfafa kwakwalwa. Shaida ta nuna cewa sau dubu ya fi ƙarfin aniracetam. Gwaje-gwaje na asibiti a cikin shekarun da suka gabata sun nuna cewa unifiram na iya haɓaka ƙwaƙwalwa da haɓaka damar iya yin amfani da hankali kamar sauran nootropics waɗanda ke racetam. Bincike ya nuna cewa unifiram ingantacciyar mai tsarin mai karɓar AMPA ce ta allosteric.

Yana aiki don rage tasirin masu adawa da NMDA, muscarinic da AMPA. AMPA da NMDA antagonist suna kwafin aiki na glutamate, kuma saboda wannan, suna da alaƙa kai tsaye da ƙwaƙwalwa da koyo a cikin kwakwalwa. Hakanan yana da ikon sarrafa shaye-shaye a cikin kwakwalwa saboda haka inganta haɓakar ƙwayar jijiyoyin neuronal. Kamar piracetam, oxiracetam, pramiracetam da noopept, yana haɓaka samar da acetylcholine.

 

Tunanin Unifiram (DM232)

 

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