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Emoxypine foda (2364-75-2)

Ana amfani da foda na Emoxipine don maganin cututtukan ƙwayar cuta na ƙananan ƙwayoyin cuta da ƙwayoyin cuta na ciki da jijiyoyin jini, angioretinopathy, tsakiya da na gefe chorioretinal dystrophy, thrombosis na ƙwayar cuta na tsakiya da reshenta, da sauransu.

Kirkira: Production Batch
Package: 1KG / jaka, 25KG / drum
Wisepowder yana da ikon samarwa da samar da adadi mai yawa. Duk samarwa a ƙarƙashin yanayin cGMP da tsarin kula da ingancin inganci, duk takaddun gwaji da samfurin akwai.
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Emoxypine foda (2364-75-2) bidiyo

 

Bayani na Emoxypine foda Base

sunan Emoxypine foda
CAS 2364-75-2
tsarki 98%
Chemical name Mezidol; Mexifin
nufin abu ɗaya ne Emoxipine, Emoxypin, Epigid, 6-Methyl-2-ethyl-3-hydroxypyridine
kwayoyin Formula C8H11NO
kwayoyin Weight 137.179 g g / mol
Ƙaddamarwa Point 170 zuwa 172 ° C
InChI Key JPGDYIGSCHWQCC-UHFFFAOYSA-N
Form m
Appearance Fari zuwa Kashe-farin foda
Rabin Rayuwa 2-2.6 hours
solubility Sosai mai narkewa cikin ruwa; DMSO (Mai kadan); Methanol (Dan kadan)
Storage Yanayin 0 - 4 C don gajere (kwanaki zuwa makonni), ko -20 C na dogon lokaci (watanni).
Aikace-aikace RAD140 mai bincike ne kuma mai maye gurbin mai karɓar inrogen (SARM) don maganin yanayi kamar ɓarkewar tsoka da cutar kansa.
Takardar Gwaji Ya Rasu

 

Emoxypine foda Janar Bayani

Emoxypine (2-ethyl-6-methyl-3-hydroxypyridine) foda, wanda kuma aka sani da Mexidol ko Mexifin lokacin da aka yi amfani dashi azaman gishiri mai maye, shine ƙirar antioxidant wanda aka ƙera a cikin Russiaby Pharmasoft Pharmaceuticals. Tsarin sunadarai ya yi kama da na pyridoxine (wani nau'in bitamin B6).

 

Emoxypine foda (2364-75-2) Tarihi

Emoxypine foda an fara kirkirar shi ta hanyar LD Smirnov da KM Dumayev, sannan yayi nazari da haɓaka a Cibiyar Magunguna, Kwalejin Kimiyya ta Rasha da Cibiyar Ilimin Kimiyya ta ofasa ta Tsaro.

 

Emoxypine (2364-75-2) Hanyar Nawa

Tsarin Emoxypine na aiki an yi imanin shine tasirinsa na antioxidant da membrane tare da abubuwan maɓallin masu zuwa:

  • Emoxypine yana hana iskar shaye shaye na lipids mai narkewa, yana mayar da martani ga peroxide radicals na lipids primary da hydroxyl raddi na peptides
  • Asesara ayyukan enzymes na antioxidant, musamman na superoxide dismutase, da alhakin samarwa da amfani da ƙwayoyin ƙwayar lipid da siffofin oxygen mai aiki.
  • Yana hana radicals kyauta yayin aikin kwayar cutar ta prostaglandin da ake kira cyclooxygenase da lipoxygenase, yana ƙaruwa da haɗin gwiwar prostacyclin / thromboxane A2and yana toshe haɓakar leukotriene
  • Theara yawan abubuwan da ke cikin murfin pola na lipids (phosphatidyl serine da phosphatidyl inositol) kuma yana rage tasirin cholesterol / phospholipids wanda ke tabbatar da kayyade-kayyade kayan maye; yana canza tsarin canzawa zuwa ƙananan bangarorin zafin jiki, wannan shine yake tsoratar da rage yawan jijiyoyin ƙwayoyi da haɓaka da haɓakar sa, yana ƙaruwa rabo mai guba.
  • Modulates aikin membrane-daure enzymes: phosphodiesterase, cyclicnucleotides, adenylate cyclase, aldoreductase, acetylcholinesterase.
  • Modulates masu rikodin ƙwayoyin kwakwalwa, watau benzodiazepine, GABA, masu karɓar acetylcholine ta hanyar ƙara ƙarfin ɗauri.
  • Yana daidaita halittun jikin mutum, watau tsarin membrane na sel na jini - erythrocytes da thrombocytes yayin haemolysis ko rauni na inji haɗe da samuwar masu ƙarancin ra'ayi.
  • Yana canza matakin monoamine kuma yana ƙara yawan abubuwan dopamine a cikin kwakwalwa.

Emoxypine (2364-75-2) Aikace-aikace

A Rasha, emoxypine yana da aikace -aikace masu yawa a cikin aikin likita. Yana da alama yana motsa damuwa, tashin hankali, anti-barasa, anticonvulsant, nootropic, neuroprotective da kuma anti-inflammatory mataki. Emoxypine mai yiwuwa yana haɓaka zagayawar jijiyoyin jini, yana hana haɗuwar thrombocyte, yana rage matakan cholesterol, yana da aikin zuciya da aikin antiatherosclerotic.

 

Emoxypine (2364-75-2) Researcharin Bincike

Studyaya daga cikin binciken ya ƙayyade tasirin emoxypine a cikin marasa lafiya na 205 tare da bayyanar cututtuka na lumbosacral radiculopathy (LSR). An raba marasa lafiya zuwa rukuni biyu, kuma ci gaba an rarraba su zuwa ɓangarorin ƙungiyoyi dangane da kasancewar tashin hankalin motar. Dukkanin marasa lafiya sun karɓi hanya na magani na al'ada da kuma ilimin motsa jiki; babban rukuni bugu da ƙari an karɓi emoxypine. Bayan haka, kulawa na asibiti-neurological na sakamakon dogon lokacin da aka samu na magani a cikin rukuni na marasa lafiya an yi shi. Sakamakon binciken ya nuna cewa yin amfani da emoxypine a cikin haɗin gwiwa na marasa lafiya tare da LSR ya haifar da raguwa da ci gaba da rage ciwo na ciwo da saurin dawo da aikin tushen jijiyoyin jijiyoyi da jijiyoyin jijiyoyi idan aka kwatanta da jiyya na al'ada.

 

Emoxypine (2364-75-2) Tunani

[1] Dumayev KM, Voronina TA, maganin antiridik na Smirnov LD a cikin prophylaxis da kuma maganin cututtukan CNS. Moscow, 1995

[2] Kucheryanu, VG (Janairu 2001). "Mexidol yana da tasirin antiparkinsonian na L-DOPA a cikin kwayar cutar Parkinsonism ta MPTP". Eksperimental'naia i klinicheskaia farmakologiia. 64 (1): 22-25.

[3] Likhacheva, EB; Sholomov, II (2006). "Bincike na asibiti da na rigakafi na ingancin mexidol a cikin maganin lumbosacral radiculopathy". ZhurnalNevrologii i Psikhiatrii Imeni SS Korsakova. 106 (10): 52-7.
 

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