pinoline foda (20315-68-8)

pinoline foda (20315-68-8) bidiyo

 

pinoline foda (20315-68-8) Base Information

sunan	pinoline foda
CAS	20315-68-8
tsarki	98%
Chemical name	6-Methoxy-1,2,3,4-tetrahydro-9H-pyrido [3,4-b] indole
nufin abu ɗaya ne	20315-68-8 6-methoxy-2,3,4,9-tetrahydro-1H-pyrido [3,4-b] indole 6-methoxytryptoline 6-Hanyar-1,2,3,4-tetrahydro-beta-carboline fil
kwayoyin Formula	C12H14N2O
kwayoyin Weight	202.257 g / mol
Ƙaddamarwa Point	216- 224 ° C
InChI Key	QYMDEOQLJUUNOF-UHFFFAOYSA-N
Form	m
Appearance
Rabin Rayuwa
solubility
Storage Yanayin
Aikace-aikace	Pinoline wani maganin methoxylated tryptoline (5-methoxytryptoline) wanda aka dade ana ikirarin samarwa a cikin ƙwayar pineal yayin metabolism na melatonin,
Takardar Gwaji	Ya Rasu

 

Babban abun kwalliya

Pinoline (6-methoxy-tetrahydro-beta-carboline) foda za a iya ƙirƙira a cikin jikin ɗan adam a ƙarƙashin yanayin ilimin lissafi daga 5-hydroxytryptamine ko azaman metric na tricyclic na melatonin. Dukansu melatonin da pinoline sun hana peroxidation na lipid kuma sun nuna aiki mai kama da juna a cikin gwajin matsayin duka antioxidant. Waɗannan sakamakon suna tallafawa mahimmancin ɓangaren ɓangaren kwayar halitta da ƙungiyar 5-methoxy gama gari ga duka mahaɗan dangane da ikon waɗannan ƙwayoyin don kashe radicals hydroxyl.

 

pinoline (20315-68-8) researcharin bincike

Kamar yadda aka nuna pinoline don yin tasirin antidepressant-like sakamako a cikin gwaje-gwajen halayyar kuma an ruwaito cewa yana da ƙarancin guba, wannan ya kamata a kara nazarin wannan a matsayin yiwuwar maganin antidepressant tare da bayyana tasirin antioxidative. Wadannan sakamakon sun kara nuna goyon baya ga mahimmancin glandon gland a cikin kariya ta kariya.

 

pinoline (20315-68-8) Tunani

1. Schiller, Erich; Bartsch, H. (2003). Free Radicals da Inhalation Pathology: Tsarin numfashi, Tsarin Mononuclear Phagocyte, Hypoxia da Reoxygenation, Pneumoconioses, da sauran Granulomatoses, Ciwon daji (Littafin Google, littafin kallo). Bazara p 107. ISBN 978-3-540-00201-7. Da aka dawo da shi 2009-02-14.
2.  Airaksinen, MM, Huang, JT, Ho, BT, Taylor, D., da Walker, K. (1978). "Uaukar 6-Methoxy-1,2,3,4-Tetrahydro-β-carboline da Tasirinsa kan 5-Hydroxytryptamine ptaukar da Saki a cikin Jinin jini". Dokar Pharmacol Toxicol. 43 (5): 375-380. Doi: 10.1111 / j.1600-0773.1978.tb02281.x.
3. Bartels, SP (2006) Amfani na Amurka A'a 20,060,292,202 Washington, DC: US
4. {Mario de la Fuente et al. 2015 "genicimar Nazarin genicwararren Neurogenic da Neurowayar Magungunan Magunguna na 6-Methoxy-1,2,3,4-tetrahydro-β-carboline (Pinoline) da Melatonin-Pinoline Hybrids" http://pubs.acs.org/doi/abs/10.1021 / akshenneuro.5b00041}