Products

NSI-189 foshat foda (1270138-41-4)

NSI-189 phosphate shine mai tayar da hankali na neurogenesis na ƙwayoyin ƙwayoyin tsohuwar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar jikin mutum a cikin sel da a cikin vivo Hakanan ana tunanin Raw NSI-189 foshate foda ne mai ba da magani don wani yanayi wanda ya haɗa da rikice-rikicen damuwa na damuwa bayan (PTSD), cutar Alzheimer da matsalolin ilimin da suka shafi tsufa.

Kirkira:  Production Batch
Package: 1KG / jaka, 25KG / drum
Wisepowder yana da ikon samarwa da samar da adadi mai yawa. Duk samarwa a ƙarƙashin yanayin cGMP da tsarin kula da ingancin inganci, duk takaddun gwaji da samfurin akwai.
category:

NSI-189 foshat foda (1270138-41-4) bidiyo

 

 

Nodi-189 phosphate Base Information

sunan NSI-189 phosphate foda
CAS 1270138-41-4
tsarki 98%
Chemical name (2-((3-Methylbutyl)amino)-3-pyridinyl)(4-(phenylmethyl)-1-piperazinyl)-methanone phosphate
nufin abu ɗaya ne NSI189 Phosphate; Nodi 189 Phosphate; NSI-189 Phosphate
kwayoyin Formula C22H33N4O5P
kwayoyin Weight 464.5
Ƙaddamarwa Point
InChI Key LWHMGALTTIYPJU-UHFFFAOYSA-N
Form foda
Appearance fararen foda
Rabin Rayuwa Rashin sani
solubility Rashin sani
Storage Yanayin Adana a 4-8 ° C
Aikace-aikace amfanin nootropic
Takardar Gwaji Ya Rasu

 

NSI-189 phosphate Bayanin Gaba ɗaya

NSI-189 phosphate shine wakilin bincike na neurogenic da nootropic wanda aka haɓaka daga nicotinamide da pyrazine.

Gwaje-gwaje da ake sarrafawa sun nuna cewa yana ƙarfafa neurogenesis ko samar da ƙwayoyin neuronal a cikin kwakwalwa. A cikin nazarin dabbobi, an kuma nuna shi don kara girman hippocampus da kashi 20% ta hakan yana sauya alamun halayen rashin kwanciyar hankali. Irin waɗannan karatun sun nuna cewa yana iya zama ingantaccen magani don ɓacin rai.

Hakanan ana tsammanin magani ne mai ban sha'awa ga sauran yanayin ciki har da rikicewar tashin hankali bayan tashin hankali (PTSD), cutar Alzheimer da matsalolin fahimi masu alaƙa da shekaru.

 

NSI-189 phosphate Hanyar Neman Aiki

Masu bincike sun gano cewa cutar-babban cuta mai juyayi (MD) -i a rage kwayawar hijabi. Ka lura cewa lafiyar hippocampus ingantacciya itace tushen ƙwayoyin ƙwayoyin jijiyoyi waɗanda ke haifar da samar da jijiyoyi. Neurons a gefe guda yana da mahimmanci don ƙirƙirar sababbin sababbin haɗi a cikin kwakwalwa. Ta hanyar samar da sababbin neurons a cikin yankin hippocampal, za'a iya bi da ciwon ciki.

An kirkiro phosphate NSI-189 don magance mahimman abubuwa guda uku na bakin ciki ciki har da ƙarar hippocampal, neurogenesis da neurotransmission. NSI-189 yana ƙara ƙarar a cikin hippocampus. A yin haka, ƙarar hippocampal da ƙwanƙolin ƙwayar ƙwayar ƙwaƙwalwar ajiya suna ƙaruwa saboda haka inganta yanayin aiki da haɓaka. Baya ga ƙarar hippocampal, maganin yana inganta aikin kwayar halitta. Yana aiki da shi don inganta ƙwanƙirar ƙwayar ƙwayar cuta yayin gyara wuraren lalacewa a cikin kwakwalwa.

 

NSI-189 foshat foda (1270138-41-4) Aikace-aikace

  1. Ingantawa cikin martanin halayen da ke da alaƙa da ɓacin rai.
  2. Komawa na ƙwanƙwasawar ƙwayar mahaifa.
  3. Zai iya haɓaka ƙwaƙwalwar ajiya da sanin yakamata ta hanyar haɓaka neurogenesis, musamman a cikin batutuwa masu rauni.
  4. Mummunan sakamako na iya tsayawa bayan an daina jinya.

 

NSI-189 foshat foda (1270138-41-4) researcharin bincike

Nazarin da aka gudanar don kimanta tasirin NSI-189 phosphate ya bayyana cewa 40 zuwa 80 MG kowace rana yana da tasiri wajen magance ɓacin rai da kuma alamun bayyanar cututtuka tsakanin masu lafiya. A cikin waɗannan gwaje-gwajen, babu wasu munanan abubuwan da suka faru. Gabaɗaya, NSI-189 phosphate yana da juriya da aminci ga amfanin ɗan adam.

 

NSI-189 foshate foda Nuna

  • 1: Papakostas GI, Johe K, Han H, Drouillard A, Russo P, Kay G, Kashambwa R, Hoeppner B, Flynn M, Yeung A, Martinson MA, Fava M. Mataki na 2, makanta biyu, karatun-sarrafa-kankara na NSI-189 foshate, mahaɗa mai ƙwaƙwalwa, a tsakanin asibitocin da ke da matsala ta rashin ƙarfi. Mol Psychiatry. 2019 Jan 9. doi: 10.1038 / s41380-018-0334-8. [Epub gabanin bugawa] PubMed PMID: 30626911.
  • 2: Liu Y, Johe K, Sun J, Hao X, Wang Y, Bi X, Baudry M. Ingantaccen ƙwaƙwalwar synaptik da sake juyewar rashin ƙarfi a cikin motar motsa jiki da aikin fahimi a cikin tsarin motsi na Angelman Syndrome ta ƙaramin ƙwaƙwalwar neurogenic, NSI -189. Neuropharmacology. 2019 Jan; 144: 337-344. doi: 10.1016 / j.neuropharm.2018.10.038. Epub 2018 Nov 5. PubMed PMID: 30408487.
  • 3: Allen BD, Acharya MM, Lu C, Giedzinski E, Chmielewski NN, Quach D, Hefferan M, Johe KK, Limoli CL. Gyarawa Radiation-Induced Cognitive Dysfunction ta hanyar Oral Administrator na Neuroprotective Compound NSI-189. Radiat Res. 2018 Apr; 189 (4): 345-353. doi: 10.1667 / RR14879.1. Epub 2018 Jan 19. Buga PMID: 29351056; PubMed Central PMCID: PMC5910029.

 

Labarai masu amfani