Tianeptine hemisulfate monohydrate (THM) foda (1224690-84-9)

THM foda (1224690-84-9) bidiyo

 

 

THM foda (1224690-84-9) Base Information

sunan	Tianeptine hemisulfate monohydrate (THM) foda
CAS	1224690-84-9
tsarki	98%
Chemical name	Tianeptine hemisulfate monohydrate; 1224690-84-9; Heptanoic acid,
nufin abu ɗaya ne	Tianeptine hemisulfate monohydrate 1224690-84-9 7 - ((3-Chloro-6-methyl-5,5-dioxido-6,11-dihydrodibenzo [c, f] [1,2] thiazepin-11-yl) amino) tarin kwayoyin acid mai narkewa tare da acid na sulfuric (2: 1) bushewar ruwa Sinadarin Tianeptine; Tianeptine-d4 BCP30653
kwayoyin Formula	C42H56Cl2N4O14S3
kwayoyin Weight	1008.01
Ƙaddamarwa Point	1800 ℃
InChI Key	KVVMXNNJBVTOSX-UHFFFAOYSA-N
Form	foda
Appearance	Farin crystalline foda
Rabin Rayuwa	Rashin sani
solubility	Creetly soluble A cikin ruwa da methanol da dichloromethane
Storage Yanayin	Tianeptine hemisulfate monohydrate foda yana da kwanciyar hankali na akalla shekaru hudu lokacin da aka adana shi kuma ba'a yanke shi a −20 ° C ba.
Aikace-aikace	Anti-ulcer da anti-kwayoyin mallaka. Labarin
Takardar Gwaji	Ya Rasu

 

THM foda (1224690-84-9) Babban bayanin

Ana amfani da sulfate na Tianeptine da farko a cikin lura da rikicewar damuwa, kodayake ana iya amfani da shi don magance asma ko ciwo na hanji. Chemically shi ne mai tricyclic antidepressant (TCA), amma yana da kaddarorin magunguna daban-daban fiye da TCAs na yau da kullun kamar yadda bincike na kwanan nan ya nuna cewa tianeptine yana haifar da tasirin antidepressant ta hanyar canji na ayyukan mai karɓar glutamate (watau masu karɓar AMPA da masu karɓar NMDA) da sakin BDNF, bi da bi shafi na tsarin filastik.

Sinadarin Tianeptine yana da magungunan antidepressant da anxiolytic (anti-damuwa) tare da rashin dangi na rashin magani, cututtukan cututtukan zuciya da cututtukan zuciya, don haka suna ba da shawarar musamman don amfani a cikin tsofaffi da kuma waɗanda ke bin karban barasa; irin waɗannan mutanen zasu iya zama mai hankali ga mummunan tasirin magungunan psychotropic. Sakamakon binciken da aka yi kwanan nan yana nuna yiwuwar anticonvulsant (anti-seizure) da kuma aikin (painkill) aikin tianeptine ta hanyar kai tsaye ko saukad da masu adenosine A1 masu karɓa (saboda tasirin zai iya dakatar da gwaji ta hanyar magabatan wannan masu karɓa).

 

THM foda (1224690-84-9) Tarihi

Tsarin Tianeptine sulfate (Tianeptine Hemisulfate Monohydrate （THM）) an rarrabe shi azaman mai zaɓin mai haɓaka ƙwaƙwalwar serotonin (SSRE) wanda aka yi amfani dashi don magance rashin damuwa. Tianeptine an haɓaka shi a Faransa a cikin 1960s kuma anyi amfani dashi a ƙarshen ƙarshen 2000s. Akwai sulfate sulfate, soda na Tianeptine, da acid acid Tianeptine.

An tsara shi azaman mai zaɓin kayan haɓaka na serotonin reuptake (SSRE) wanda aka yi amfani dashi don magance ɓacin rai. Tianeptine an haɓaka shi a Faransa a cikin 1960s kuma anyi amfani dashi a ƙarshen ƙarshen 2000s. Akwai sulfate sulfate, soda na Tianeptine, da acid acid Tianeptine.

 

THM foda (1224690-84-9) Hanyar Nawa

Ba kamar yawancin antidepressants ba, Tianeptine yana da ƙananan tasirin illa; Tianeptine yana nuna alƙawari a matsayin madadin masu maganin ƙwaƙwalwar gargajiyar gargajiya da halayensu na jaraba da jerin abubuwan da ke haifar dasu.Yayin da yawancin masu amfani da maganin ba sa zagi ko amfani da magungunan, an ba su umarnin, wannan ba ya magana da sauran jama'a. . Magungunan kwantar da hankali sanannen aiki ne na haɗari. Ga mutanen da ba sa buƙatar su, shan irin waɗannan ƙwayoyi na iya zuwa da illoli masu yawa da yawa da kuma haɗarin kayan maye. Tianeptine na iya zama madadin mafi aminci ga yawancin antidepressants da ke kasuwa a yau. Lissafin cututtukan da ke tattare da su ƙananan ne kuma ana iya jure su, sun haɗa da bacci, bushe-bushe, rashin bacci, jiri, jiri, maƙarƙashiya, ƙarancin hawan jini, kuma wasu marasa lafiya suna kwatanta mafarkai masu ban mamaki.

 

THM foda (1224690-84-9) Aikace-aikace

Magungunan Tianeptine don magance cututtukan kwakwalwa, bincike sun nuna cewa tianeptine ba kawai kyakkyawan sakamako na antidepressant da halayen haɗari sun kasance ƙasa da ƙananan magungunan maganin tricyclic na al'ada, kusan babu mummunar tasiri akan tsarin jijiyoyin jini, jini, hanta da aikin koda ba a cutar da su ba. , kuma ba ni da nutsuwa. Tianeptine ba kawai tasiri bane don bacin rai da nakasa mai narkewa, rashin shan giya da bacin rai bayan shan giya shima yana da tasiri. Amfani da na dogon lokaci na iya hana sake komawa

 

THM foda (1224690-84-9) researcharin bincike

Anyi nazarin Magnesium ta beraye don jinkirta farawa da ci gaban cututtukan cataract.

Hakanan ana amfani da Tianeptine don magance rikicewar damuwa, asma har ma da rashin damuwa na hanji.

Kimiyya A bayan Sa:

wannan tambaya ce mai ruɗi saboda Tianeptine sulfate shine sabon fili wanda ke buƙata, kuma ya cancanci, ƙarin kudaden da aka saka a ciki don gwaji.

Abin da muka sani shi ne cewa Tianeptine Sulfate yana da alaƙa da Tianeptine Sodium, kuma yana aikatawa sosai. wannan ya faru ne saboda bambancin tsarin sunadarai, kamar yadda za'a iya gani a adadi ta hannun dama.

ga waɗanda daga cikinku suka saba da Tianeptine Sodium, ƙila ku san shi a ƙarƙashin sunan kasuwanci & lsquo; Coaxil 'ta hanyar Turai da Asiya ko kuma & lsquo; Stablon 'da & lsquo; Tatinol 'ta Latin Amurka. a halin yanzu an yarda dashi don amfani da lafiya a ƙasashe 20.

Abin mamaki, kodayake, masana kimiyya ba su da tabbaci 100% game da yadda Tianeptine yake a zahiri & lsquo; yana aiki. Tunanin farko shine cewa yayi aiki ne a matsayin mai Ingantaccen Serotonin Re-absorption Enhancer (SSRE) duk da haka binciken da aka yi kwanan nan ya nuna cewa ainihin lokacin ba shi da tasiri akan tsarin mulkin ƙasa wanda zai iya inganta matakan serotonin.

Sabbin ka'idoji game da aikin Tianeptine azaman maganin rigakafi ta hanyar canza ayyukan mai karɓar glutamate kai tsaye da kuma sakin BDNF (ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwa) wanda zai iya jujjuya yanayin jijiyoyin jiki.

akwai kuma wani sabon bincike a cikin Yulin 2014 wanda ya gano cewa Tianeptine ita ce mai azabar kai tsaye na Masu karɓar Mu da Delta Opioid. tunda ana alakanta masu karɓa na Mu-Opioid zuwa tasirin euphoric, wannan an ba da shawarar a matsayin dalili na aikin Tianeptine a matsayin mai hana tashin hankali.

 

THM foda (1224690-84-9) Tunani

• Tianeptine hemisulfate monohydrate