Nooglutyl foda (112193-35-8)

Nooglutyl foda (112193-35-8) bidiyo

 

 

Nooglutyl foda (112193-35-8) Labarin Base

sunan	Nooglutyl foda
CAS	112193-35-8
tsarki	98%
Chemical name	N - [(5-Hydroxy-3-pyridinyl) carbonyl] -L-glutamic acid N- (5-hydroxynicotinoyl) -L-glutamic acid N- (5-Hydroxymethyl-pyridin-2-yl) -2,2-dimethyl-propionamide ； nooglutil
nufin abu ɗaya ne	nooglutil;N-[(5-Hydroxy-3-pyridinyl)carbonyl]-L-glutamic acid;N-[(5-Hydroxypyridin-3-yl)carbonyl]-L-glutamicacid;ONK-10;L-GlutaMic acid, N-[(5-hydroxy-3-pyridinyl)carbonyl]-;Nooglutyl
kwayoyin Formula	C11H12N2O6
kwayoyin Weight	268.22 g / mol
Ƙaddamarwa Point	N / A
InChI Key	XFZGYOJFPGPYCS-QMMMGPOBSA-N
Form	m
Appearance	Farar lafiya foda
Rabin Rayuwa	30 minti zuwa 3 hours
solubility	kadan soluble a cikin ruwa da kuma ethanol.
Storage Yanayin	Adana a cikin sanyi mai bushe da bushe, an kiyaye shi daga danshi da haske mai ƙarfi ko zazzabi mai zafi.
Aikace-aikace	An yi amfani da shi a cikin magani, kayayyakin kiwon lafiya, abinci, abin sha, kayan shafawa, abubuwan nazarin halittu da sinadarai da sauran masana'antu.
Takardar Gwaji	Ya Rasu

 

Nooglutyl foda (112193-35-8) Babban bayanin

Nooglutyl wakili ne na kwayar halitta wanda ake karantawa a Cibiyar Nazarin Magungunan Magunguna, Kwalejin Kimiyyar Kiwon Lafiya ta Rasha a matsayin maganin cutar amnesia. A cikin sifofin dabbobi, yana da nau'ikan tasirin tsarin juyayi na tsakiya.

Gwaje-gwaje a kan berayen suna nuna cewa nooglutyl yana nuna alamomi masu karewa-kariya masu kariya kuma ta wurin aikin antimotion ba ya samuwa a ƙarƙashin masu tsaron gida na musamman, irin su scopolamine da diprazine. Nazarin ilimin electrophyysiological a kan garuruwa ya nuna cewa nooglutyl ya canza aiki mai ban sha'awa a 80% na ƙananan ƙananan ƙwayoyin cuta (yankin somatosensory I da yanki na 5 na ɓangaren ƙungiyar tarayya) da kuma mummunar tasirin da lalacewa ta hanyar motsi motsi: kunna aiki na ɗaya na zone na somatosensory I da kuma hanawa neuron amsa zuwa somatic stimulation. An kiyasta wannan kayan aikin shiri don samar da asali na tasirin antimotion.

 

Nooglutyl foda (112193-35-8) Tarihi

Nooglutyl wakili ne na nootropic wanda aka yi karatu a Cibiyar Nazarin Magunguna na Farmacology, Kwalejin Kimiyya ta Rasha a matsayin yiwuwar magani ga amnesia.Dukkan dabbobi, yana da nau'ikan tasirin tsarin juyayi na tsakiya.

 

Nooglutyl foda (112193-35-8) Hanyar Neman Aiki

Gwaje-gwaje a kan berayen suna nuna cewa nooglutyl yana nuna alamomi masu karewa-kariya masu kariya kuma ta wurin aikin antimotion ba ya samuwa a ƙarƙashin masu tsaron gida na musamman, irin su scopolamine da diprazine. Nazarin ilimin electrophyysiological a kan garuruwa ya nuna cewa nooglutyl ya canza aiki mai ban sha'awa a 80% na ƙananan ƙananan ƙwayoyin cuta (yankin somatosensory I da yanki na 5 na ɓangaren ƙungiyar tarayya) da kuma mummunar tasirin da lalacewa ta hanyar motsi motsi: kunna aiki na ɗaya na zone na somatosensory I da kuma hanawa neuron amsa zuwa somatic stimulation. An kiyasta wannan kayan aikin shiri don samar da asali na tasirin antimotion.

 

Nooglutyl foda (112193-35-8) Aikace-aikacen

Nooglutyl wakili ne na kwayar halitta wanda ake karantawa a Cibiyar Nazarin Magungunan Magunguna, Kwalejin Kimiyya ta Kiwon Lafiya ta Rasha a matsayin magani na amnesia.

 

Nooglutyl foda (112193-35-8) Tunani

• Flekhter, Oxana B. (2000). "Nooglutil, Kwalejin Kwalejin Kimiyya ta Rasha". Sanarwa ta yanzu a cikin Magungunan Binciken Tsarin Tsarin Tsarin Tsarin Tsarin Tsarin Tsarin Tsarin Tsarin Tsarin Tsarin Tsarin Tsarin Tsarin Tsarin Tsarin Tsarin Tsarin Tsarin Tsarin Tsarin Tsarin Tsarin Tsarin Tsarin Tsarin Tsarin Tsarin Tsarin Tsarin Tsarin Tsarin Tsarin Tsarin Tsarin Tsarin Tsarin Tsarin Tsarin Tsarin Tsarin Tsarin Tsarin Tsarin Tsarin Tsarin Tsarin Tsarin Tsarin Tsarin Tsarin Tsarin Tsarin Tsarin Tsarin Magunguna 2 (4): 491–
• V. Yasnetsov; VA Pravdivtsev; VM Popov; TA Voronina; NM Kiseleva; SB Kozlov (Mayu 1995). "Tasirin Antimotion na Nooglutyl da Tsarin Neuronal". Sanarwa game da Gwajin Biology da Magani. 119 (5): 515-516. Doi: 10.1007 / BF02543440. PMID 7579248. An dawo da shi 2011-02-08.
• Voronina, TA; Borlikova, GG; Garibova, TL; Proskuryakova, TV; Petrichenko, OB; Burd, SG; Avakyan, GN (2002). "Tasirin nooglutil akan cutar ciwon benzodiazepine da ɗaukar 3H-spiperone tare da masu karɓar D2 a cikin rat striatum". Sanarwa game da ilmin gwaji da magani. 134 (5): 448–